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Open access
Diagnostics, volume 11, issue 2, pages 267

Laser doppler spectrum analysis based on calculation of cumulative sums detects changes in skin capillary blood flow in type 2 diabetes mellitus

Publication typeJournal Article
Publication date2021-02-09
Journal: Diagnostics
Quartile SCImago
Q2
Quartile WOS
Q2
Impact factor3.6
ISSN20754418
Clinical Biochemistry
Abstract

In this article, we introduce a new method of signal processing and data analysis for the digital laser Doppler flowmetry. Our approach is based on the calculation of cumulative sums over the registered Doppler power spectra. The introduced new parameter represents an integral estimation for the redistribution of moving red blood cells over the range of speed. The prototype of the device implementing the technique is developed and tested in preliminary clinical trials. The methodology was verified with the involvement of two age groups of healthy volunteers and in a group of patients with type 2 diabetes mellitus. The main practical result of the study is the development of a set of binary linear classifiers that allow the method to identify typical patterns of the microcirculation for the healthy volunteers and diabetic patients based on the presented diagnostic algorithm.

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GOST |
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GOST Copy
Kozlov I. et al. Laser doppler spectrum analysis based on calculation of cumulative sums detects changes in skin capillary blood flow in type 2 diabetes mellitus // Diagnostics. 2021. Vol. 11. No. 2. p. 267.
GOST all authors (up to 50) Copy
Kozlov I., Zherebtsov E. A., Masalygina G., Podmasteryev K., Dunaev A. Laser doppler spectrum analysis based on calculation of cumulative sums detects changes in skin capillary blood flow in type 2 diabetes mellitus // Diagnostics. 2021. Vol. 11. No. 2. p. 267.
RIS |
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RIS Copy
TY - JOUR
DO - 10.3390/diagnostics11020267
UR - https://doi.org/10.3390%2Fdiagnostics11020267
TI - Laser doppler spectrum analysis based on calculation of cumulative sums detects changes in skin capillary blood flow in type 2 diabetes mellitus
T2 - Diagnostics
AU - Masalygina, Galina
AU - Dunaev, Andrey
AU - Podmasteryev, Konstantin
AU - Kozlov, Igor
AU - Zherebtsov, Evgeny A.
PY - 2021
DA - 2021/02/09 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 267
IS - 2
VL - 11
PMID - 33572387
SN - 2075-4418
ER -
BibTex |
Cite this
BibTex Copy
@article{2021_Kozlov
author = {Galina Masalygina and Andrey Dunaev and Konstantin Podmasteryev and Igor Kozlov and Evgeny A. Zherebtsov},
title = {Laser doppler spectrum analysis based on calculation of cumulative sums detects changes in skin capillary blood flow in type 2 diabetes mellitus},
journal = {Diagnostics},
year = {2021},
volume = {11},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {feb},
url = {https://doi.org/10.3390%2Fdiagnostics11020267},
number = {2},
pages = {267},
doi = {10.3390/diagnostics11020267}
}
MLA
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MLA Copy
Kozlov, Igor, et al. “Laser doppler spectrum analysis based on calculation of cumulative sums detects changes in skin capillary blood flow in type 2 diabetes mellitus.” Diagnostics, vol. 11, no. 2, Feb. 2021, p. 267. https://doi.org/10.3390%2Fdiagnostics11020267.
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