Open Access
Open access
volume 21 issue 23 pages 9159

Versatile Types of Polysaccharide-Based Drug Delivery Systems: From Strategic Design to Cancer Therapy

Yanzhen Sun 1
Xiaodong Jing 1
Xiaoli Ma 2
Yinglong Feng 1
Hao Hu 1
Publication typeJournal Article
Publication date2020-12-01
scimago Q1
wos Q1
SJR1.273
CiteScore9.0
Impact factor4.9
ISSN16616596, 14220067
PubMed ID:  33271967
Catalysis
Organic Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Computer Science Applications
Spectroscopy
Molecular Biology
General Medicine
Abstract

Chemotherapy is still the most direct and effective means of cancer therapy nowadays. The proposal of drug delivery systems (DDSs) has effectively improved many shortcomings of traditional chemotherapy drugs. The technical support of DDSs lies in their excellent material properties. Polysaccharides include a series of natural polymers, such as chitosan, hyaluronic acid, and alginic acid. These polysaccharides have good biocompatibility and degradability, and they are easily chemical modified. Therefore, polysaccharides are ideal candidate materials to construct DDSs, and their clinical application prospects have been favored by researchers. On the basis of versatile types of polysaccharides, this review elaborates their applications from strategic design to cancer therapy. The construction and modification methods of polysaccharide-based DDSs are specifically explained, and the latest research progress of polysaccharide-based DDSs in cancer therapy are also summarized. The purpose of this review is to provide a reference for the design and preparation of polysaccharide-based DDSs with excellent performance.

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GOST |
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GOST Copy
Sun Y. et al. Versatile Types of Polysaccharide-Based Drug Delivery Systems: From Strategic Design to Cancer Therapy // International Journal of Molecular Sciences. 2020. Vol. 21. No. 23. p. 9159.
GOST all authors (up to 50) Copy
Sun Y., Jing X., Ma X., Feng Y., Hu H. Versatile Types of Polysaccharide-Based Drug Delivery Systems: From Strategic Design to Cancer Therapy // International Journal of Molecular Sciences. 2020. Vol. 21. No. 23. p. 9159.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.3390/ijms21239159
UR - https://doi.org/10.3390/ijms21239159
TI - Versatile Types of Polysaccharide-Based Drug Delivery Systems: From Strategic Design to Cancer Therapy
T2 - International Journal of Molecular Sciences
AU - Sun, Yanzhen
AU - Jing, Xiaodong
AU - Ma, Xiaoli
AU - Feng, Yinglong
AU - Hu, Hao
PY - 2020
DA - 2020/12/01
PB - MDPI
SP - 9159
IS - 23
VL - 21
PMID - 33271967
SN - 1661-6596
SN - 1422-0067
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2020_Sun,
author = {Yanzhen Sun and Xiaodong Jing and Xiaoli Ma and Yinglong Feng and Hao Hu},
title = {Versatile Types of Polysaccharide-Based Drug Delivery Systems: From Strategic Design to Cancer Therapy},
journal = {International Journal of Molecular Sciences},
year = {2020},
volume = {21},
publisher = {MDPI},
month = {dec},
url = {https://doi.org/10.3390/ijms21239159},
number = {23},
pages = {9159},
doi = {10.3390/ijms21239159}
}
MLA
Cite this
MLA Copy
Sun, Yanzhen, et al. “Versatile Types of Polysaccharide-Based Drug Delivery Systems: From Strategic Design to Cancer Therapy.” International Journal of Molecular Sciences, vol. 21, no. 23, Dec. 2020, p. 9159. https://doi.org/10.3390/ijms21239159.