Open Access
Open access
volume 22 issue 12 pages 6229

The Combination of Liposomes and Metallic Nanoparticles as Multifunctional Nanostructures in the Therapy and Medical Imaging—A Review

Marika Musielak 1, 2, 3
Jakub Potoczny 4
Agnieszka Boś Liedke 3
M. Kozak 3
2
 
Radiobiology Laboratory, Department of Medical Physics, Greater Poland Cancer Centre, 61-866 Poznań, Poland
4
 
Heliodor Swiecicki Clinical Hospital in Poznan, 60-355 Poznań, Poland
Publication typeJournal Article
Publication date2021-06-09
scimago Q1
wos Q1
SJR1.273
CiteScore9.0
Impact factor4.9
ISSN16616596, 14220067
PubMed ID:  34207682
Catalysis
Organic Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Computer Science Applications
Spectroscopy
Molecular Biology
General Medicine
Abstract

Nanotechnology has introduced a new quality and has definitely developed the possibilities of treating and diagnosing various diseases. One of the scientists’ interests is liposomes and metallic nanoparticles (LipoMNPs)—the combination of which has introduced new properties and applications. However, the field of creating hybrid nanostructures consisting of liposomes and metallic nanoparticles is relatively little understood. The purpose of this review was to compile the latest reports in the field of treatment and medical imaging using of LipoMNPs. The authors focused on presenting this issue in the direction of improving the used conventional treatment and imaging methods. Most of all, the nature of bio-interactions between nanostructures and cells is not sufficiently taken into account. As a result, overcoming the existing limitations in the implementation of such solutions in the clinic is difficult. We concluded that hybrid nanostructures are used in a very wide range, especially in the treatment of cancer and magnetic resonance imaging. There were also solutions that combine treatments with simultaneous imaging, creating a theragnostic approach. In the future, researchers should focus on the description of the biological interactions and the long-term effects of the nanostructures to use LipoMNPs in the treatment of patients.

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GOST |
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GOST Copy
Musielak M. et al. The Combination of Liposomes and Metallic Nanoparticles as Multifunctional Nanostructures in the Therapy and Medical Imaging—A Review // International Journal of Molecular Sciences. 2021. Vol. 22. No. 12. p. 6229.
GOST all authors (up to 50) Copy
Musielak M., Potoczny J., Boś Liedke A., Kozak M. The Combination of Liposomes and Metallic Nanoparticles as Multifunctional Nanostructures in the Therapy and Medical Imaging—A Review // International Journal of Molecular Sciences. 2021. Vol. 22. No. 12. p. 6229.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.3390/ijms22126229
UR - https://doi.org/10.3390/ijms22126229
TI - The Combination of Liposomes and Metallic Nanoparticles as Multifunctional Nanostructures in the Therapy and Medical Imaging—A Review
T2 - International Journal of Molecular Sciences
AU - Musielak, Marika
AU - Potoczny, Jakub
AU - Boś Liedke, Agnieszka
AU - Kozak, M.
PY - 2021
DA - 2021/06/09
PB - MDPI
SP - 6229
IS - 12
VL - 22
PMID - 34207682
SN - 1661-6596
SN - 1422-0067
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2021_Musielak,
author = {Marika Musielak and Jakub Potoczny and Agnieszka Boś Liedke and M. Kozak},
title = {The Combination of Liposomes and Metallic Nanoparticles as Multifunctional Nanostructures in the Therapy and Medical Imaging—A Review},
journal = {International Journal of Molecular Sciences},
year = {2021},
volume = {22},
publisher = {MDPI},
month = {jun},
url = {https://doi.org/10.3390/ijms22126229},
number = {12},
pages = {6229},
doi = {10.3390/ijms22126229}
}
MLA
Cite this
MLA Copy
Musielak, Marika, et al. “The Combination of Liposomes and Metallic Nanoparticles as Multifunctional Nanostructures in the Therapy and Medical Imaging—A Review.” International Journal of Molecular Sciences, vol. 22, no. 12, Jun. 2021, p. 6229. https://doi.org/10.3390/ijms22126229.