Open Access
PAMAM-calix-dendrimers: Synthesis and Thiacalixarene Conformation Effect on DNA Binding
Тип публикации: Journal Article
Дата публикации: 2021-11-02
scimago Q1
wos Q1
БС1
SJR: 1.273
CiteScore: 9.0
Impact factor: 4.9
ISSN: 16616596, 14220067
PubMed ID:
34769329
Catalysis
Organic Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Computer Science Applications
Spectroscopy
Molecular Biology
General Medicine
Краткое описание
A convenient method for the synthesis of the first generation PAMAM dendrimers based on the thiacalix[4]arene has been developed for the first time. Three new PAMAM-calix-dendrimers with the macrocyclic core in cone, partial cone, and 1,3-alternate conformations were obtained with high yields. The interaction of the obtained compounds with salmon sperm DNA resulted in the formation of the associates of the size up to 200 nm, as shown by the UV-Vis spectroscopy, DLS, and TEM. It was demonstrated by the CD method that the structure of the DNA did not undergo significant changes upon binding. The PAMAM-calix-dendrimer based on the macrocycle in cone conformation stabilized DNA and prevented its degradation.
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ГОСТ
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Mostovaya O. et al. PAMAM-calix-dendrimers: Synthesis and Thiacalixarene Conformation Effect on DNA Binding // International Journal of Molecular Sciences. 2021. Vol. 22. No. 21. p. 11901.
ГОСТ со всеми авторами (до 50)
Скопировать
Mostovaya O., Padnya P., Shiabiev I., Mukhametzyanov T., Stoikov I. PAMAM-calix-dendrimers: Synthesis and Thiacalixarene Conformation Effect on DNA Binding // International Journal of Molecular Sciences. 2021. Vol. 22. No. 21. p. 11901.
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RIS
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TY - JOUR
DO - 10.3390/ijms222111901
UR - https://doi.org/10.3390/ijms222111901
TI - PAMAM-calix-dendrimers: Synthesis and Thiacalixarene Conformation Effect on DNA Binding
T2 - International Journal of Molecular Sciences
AU - Mostovaya, Olga
AU - Padnya, Pavel
AU - Shiabiev, Igor
AU - Mukhametzyanov, Timur
AU - Stoikov, Ivan
PY - 2021
DA - 2021/11/02
PB - MDPI
SP - 11901
IS - 21
VL - 22
PMID - 34769329
SN - 1661-6596
SN - 1422-0067
ER -
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BibTex (до 50 авторов)
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@article{2021_Mostovaya,
author = {Olga Mostovaya and Pavel Padnya and Igor Shiabiev and Timur Mukhametzyanov and Ivan Stoikov},
title = {PAMAM-calix-dendrimers: Synthesis and Thiacalixarene Conformation Effect on DNA Binding},
journal = {International Journal of Molecular Sciences},
year = {2021},
volume = {22},
publisher = {MDPI},
month = {nov},
url = {https://doi.org/10.3390/ijms222111901},
number = {21},
pages = {11901},
doi = {10.3390/ijms222111901}
}
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MLA
Скопировать
Mostovaya, Olga, et al. “PAMAM-calix-dendrimers: Synthesis and Thiacalixarene Conformation Effect on DNA Binding.” International Journal of Molecular Sciences, vol. 22, no. 21, Nov. 2021, p. 11901. https://doi.org/10.3390/ijms222111901.