Open Access
The Emerging Role of Ionic Liquid-Based Approaches for Enhanced Skin Permeation of Bioactive Molecules: A Snapshot of the Past Couple of Years
1
Publication type: Journal Article
Publication date: 2021-11-05
scimago Q1
wos Q1
SJR: 1.273
CiteScore: 9.0
Impact factor: 4.9
ISSN: 16616596, 14220067
PubMed ID:
34769430
Catalysis
Organic Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Computer Science Applications
Spectroscopy
Molecular Biology
General Medicine
Abstract
Topical and transdermal delivery systems are of undeniable significance and ubiquity in healthcare, to facilitate the delivery of active pharmaceutical ingredients, respectively, onto or across the skin to enter systemic circulation. From ancient ointments and potions to modern micro/nanotechnological devices, a variety of approaches has been explored over the ages to improve the skin permeation of diverse medicines and cosmetics. Amongst the latest investigational dermal permeation enhancers, ionic liquids have been gaining momentum, and recent years have been prolific in this regard. As such, this review offers an outline of current methods for enhancing percutaneous permeation, highlighting selected reports where ionic liquid-based approaches have been investigated for this purpose. Future perspectives on use of ionic liquids for topical delivery of bioactive peptides are also presented.
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39
Total citations:
39
Citations from 2025:
9
(23.08%)
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GOST
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Gomes A. et al. The Emerging Role of Ionic Liquid-Based Approaches for Enhanced Skin Permeation of Bioactive Molecules: A Snapshot of the Past Couple of Years // International Journal of Molecular Sciences. 2021. Vol. 22. No. 21. p. 11991.
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Gomes A., Aguiar L., Ferraz R., Teixeira C., Gomes P. S. C. The Emerging Role of Ionic Liquid-Based Approaches for Enhanced Skin Permeation of Bioactive Molecules: A Snapshot of the Past Couple of Years // International Journal of Molecular Sciences. 2021. Vol. 22. No. 21. p. 11991.
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RIS
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TY - JOUR
DO - 10.3390/ijms222111991
UR - https://doi.org/10.3390/ijms222111991
TI - The Emerging Role of Ionic Liquid-Based Approaches for Enhanced Skin Permeation of Bioactive Molecules: A Snapshot of the Past Couple of Years
T2 - International Journal of Molecular Sciences
AU - Gomes, Ana
AU - Aguiar, Luísa
AU - Ferraz, Ricardo
AU - Teixeira, Cátia
AU - Gomes, P S. C.
PY - 2021
DA - 2021/11/05
PB - MDPI
SP - 11991
IS - 21
VL - 22
PMID - 34769430
SN - 1661-6596
SN - 1422-0067
ER -
Cite this
BibTex (up to 50 authors)
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@article{2021_Gomes,
author = {Ana Gomes and Luísa Aguiar and Ricardo Ferraz and Cátia Teixeira and P S. C. Gomes},
title = {The Emerging Role of Ionic Liquid-Based Approaches for Enhanced Skin Permeation of Bioactive Molecules: A Snapshot of the Past Couple of Years},
journal = {International Journal of Molecular Sciences},
year = {2021},
volume = {22},
publisher = {MDPI},
month = {nov},
url = {https://doi.org/10.3390/ijms222111991},
number = {21},
pages = {11991},
doi = {10.3390/ijms222111991}
}
Cite this
MLA
Copy
Gomes, Ana, et al. “The Emerging Role of Ionic Liquid-Based Approaches for Enhanced Skin Permeation of Bioactive Molecules: A Snapshot of the Past Couple of Years.” International Journal of Molecular Sciences, vol. 22, no. 21, Nov. 2021, p. 11991. https://doi.org/10.3390/ijms222111991.