Combined Modification of Fiber Materials by Enzymes and Metal Nanoparticles for Chemical and Biological Protection
To obtain fiber materials with pronounced chemical-biological protection, metal (Zn or Ta) nanoparticles were jointly applied with polyelectrolyte complexes of enzymes and polypeptides being their stabilizers. Computer modeling revealed the preferences between certain polyelectrolyte partners for N-acyl-homoserine lactone acylase and hexahistidine-tagged organophosphorus hydrolase (His6-OPH) possessing the quorum quenching (QQ) behavior with bacterial cells. The combinations of metal nanoparticles and enzymes appeared to function better as compared to the combinations of the same QQ-enzymes with antibiotics (polymyxins), making it possible to decrease the applied quantities by orders of magnitude while giving the same effect. The elimination of Gram-positive and Gram-negative bacterial cells from doubly modified fiber materials notably increased (up to 2.9-fold), whereas His6-OPH retained its hydrolytic activity in reaction with organophosphorus compounds (up to 74% of initially applied activity). Materials with the certain enzyme and Zn nanoparticles were more efficient against Bacillus subtilis cells (up to 2.1-fold), and Ta nanoparticles acted preferentially against Escherichia coli (up to 1.5-fold). Some materials were proved to be more suitable for combined modification by metal nanoparticles and His6-OPH complexes as antimicrobial protectants.
Citations by journals
1
2
|
|
International Journal of Molecular Sciences
|
International Journal of Molecular Sciences
2 publications, 16.67%
|
Journal of NBC Protection Corps
|
Journal of NBC Protection Corps, 2, 16.67%
Journal of NBC Protection Corps
2 publications, 16.67%
|
Fibers
|
Fibers
1 publication, 8.33%
|
Chemosensors
|
Chemosensors
1 publication, 8.33%
|
Polymers
|
Polymers
1 publication, 8.33%
|
Coatings
|
Coatings
1 publication, 8.33%
|
Catalysts
|
Catalysts
1 publication, 8.33%
|
International Journal of Biological Macromolecules
|
International Journal of Biological Macromolecules
1 publication, 8.33%
|
Journal of Functional Biomaterials
|
Journal of Functional Biomaterials
1 publication, 8.33%
|
Lomonosov chemistry journal
|
Lomonosov chemistry journal
1 publication, 8.33%
|
1
2
|
Citations by publishers
1
2
3
4
5
6
7
8
|
|
Multidisciplinary Digital Publishing Institute (MDPI)
|
Multidisciplinary Digital Publishing Institute (MDPI)
8 publications, 66.67%
|
27 Science Center
|
27 Science Center, 2, 16.67%
27 Science Center
2 publications, 16.67%
|
Elsevier
|
Elsevier
1 publication, 8.33%
|
Moscow University Press
|
Moscow University Press
1 publication, 8.33%
|
1
2
3
4
5
6
7
8
|
- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.