Open Access
Triazavirin—A Novel Effective Antiviral Drug
Alexey I. Nemytov
1, 2
,
Vladimir L. Rusinov
1, 2
,
Mikhail V Varaksin
1, 2
,
Evgeny N Ulomskiy
1, 2
,
Ilya I Butorin
1
,
Weijie Du
3
,
Zhiyong Sun
3
,
Valery Charushin
1, 2
Publication type: Journal Article
Publication date: 2022-11-22
scimago Q1
wos Q1
SJR: 1.273
CiteScore: 9.0
Impact factor: 4.9
ISSN: 16616596, 14220067
PubMed ID:
36498864
Catalysis
Organic Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Computer Science Applications
Spectroscopy
Molecular Biology
General Medicine
Abstract
This review outlines the data of numerous studies relating to the broad-spectrum antiviral drug Triazavirin that was launched on the Russian pharmaceutical market in 2014 as an anti-influenza drug (the international non-patented name is Riamilovir). The range of antiviral activity of Triazavirin has been significantly expanded during recent years; in particular, it has been shown that Triazavirin exhibits activity against tick-borne encephalitis, Rift Valley fever, West Nile fever, and other infections of viral etiology. This drug has been approved for treatment of influenza and acute respiratory infections by the Russian Ministry of Health on the basis of comprehensive clinical trials involving over 450 patients. Triazavirin was found to be a highly effective and well-tolerated drug, allowing its over-the-counter sale. The recently published data on the use of Triazavirin in clinical practice for the treatment of patients with COVID-19 are discussed, with special attention paid to potential biological targets for this drug.
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Metrics
31
Total citations:
31
Citations from 2024:
24
(77.42%)
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MLA
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GOST
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Nemytov A. I. et al. Triazavirin—A Novel Effective Antiviral Drug // International Journal of Molecular Sciences. 2022. Vol. 23. No. 23. p. 14537.
GOST all authors (up to 50)
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Nemytov A. I., Rusinov V. L., Varaksin M. V., Ulomskiy E. N., Savateev K. V., Butorin I. I., Du W., Sun Z., Charushin V. Triazavirin—A Novel Effective Antiviral Drug // International Journal of Molecular Sciences. 2022. Vol. 23. No. 23. p. 14537.
Cite this
RIS
Copy
TY - JOUR
DO - 10.3390/ijms232314537
UR - https://doi.org/10.3390/ijms232314537
TI - Triazavirin—A Novel Effective Antiviral Drug
T2 - International Journal of Molecular Sciences
AU - Nemytov, Alexey I.
AU - Rusinov, Vladimir L.
AU - Varaksin, Mikhail V
AU - Ulomskiy, Evgeny N
AU - Savateev, Konstantin V
AU - Butorin, Ilya I
AU - Du, Weijie
AU - Sun, Zhiyong
AU - Charushin, Valery
PY - 2022
DA - 2022/11/22
PB - MDPI
SP - 14537
IS - 23
VL - 23
PMID - 36498864
SN - 1661-6596
SN - 1422-0067
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2022_Nemytov,
author = {Alexey I. Nemytov and Vladimir L. Rusinov and Mikhail V Varaksin and Evgeny N Ulomskiy and Konstantin V Savateev and Ilya I Butorin and Weijie Du and Zhiyong Sun and Valery Charushin},
title = {Triazavirin—A Novel Effective Antiviral Drug},
journal = {International Journal of Molecular Sciences},
year = {2022},
volume = {23},
publisher = {MDPI},
month = {nov},
url = {https://doi.org/10.3390/ijms232314537},
number = {23},
pages = {14537},
doi = {10.3390/ijms232314537}
}
Cite this
MLA
Copy
Nemytov, Alexey I., et al. “Triazavirin—A Novel Effective Antiviral Drug.” International Journal of Molecular Sciences, vol. 23, no. 23, Nov. 2022, p. 14537. https://doi.org/10.3390/ijms232314537.
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