Open Access
International Journal of Molecular Sciences, volume 24, issue 8, pages 6882
Exploring the Conformational Equilibrium of Mefenamic Acid Released from Silica Aerogels via NMR Analysis
1
3
Molecular Physical-Chemistry R&D Unit, Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal
|
Publication type: Journal Article
Publication date: 2023-04-07
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 5.6
ISSN: 16616596, 14220067
PubMed ID:
37108046
Catalysis
Organic Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Computer Science Applications
Spectroscopy
Molecular Biology
General Medicine
Abstract
This study examines the influence of mefenamic acid on the physical and chemical properties of silica aerogels, as well as its effect on the sorption characteristics of the composite material. Solid state magic angle spinning nuclear magnetic resonance (MAS NMR) and high-pressure 13C NMR kinetic studies were conducted to identify the presence of mefenamic acid and measure the kinetic rates of CO2 sorption. Additionally, a high-pressure T1–T2 relaxation-relaxation correlation spectroscopy (RRCOSY) study was conducted to estimate the relative amount of mefenamic acid in the aerogel’s pores, and a high-pressure nuclear Overhauser effect spectoscopy (NOESY) study was conducted to investigate the conformational preference of mefenamic acid released from the aerogel. The results indicate that mefenamic acid is affected by the chemical environment of the aerogel, altering the ratio of mefenamic acid conformers from 75% to 25% in its absence to 22% to 78% in the presence of aerogel.
Citations by journals
|
1
2
|
|
|
Journal of Molecular Liquids
|
Journal of Molecular Liquids
2 publications, 33.33%
|
|
Membranes
|
Membranes
1 publication, 16.67%
|
|
Crystals
|
Crystals
1 publication, 16.67%
|
|
ACS applied materials & interfaces
|
ACS applied materials & interfaces
1 publication, 16.67%
|
|
Industrial & Engineering Chemistry Research
|
Industrial & Engineering Chemistry Research
1 publication, 16.67%
|
|
1
2
|
Citations by publishers
|
1
2
|
|
|
Elsevier
|
Elsevier
2 publications, 33.33%
|
|
Multidisciplinary Digital Publishing Institute (MDPI)
|
Multidisciplinary Digital Publishing Institute (MDPI)
2 publications, 33.33%
|
|
American Chemical Society (ACS)
|
American Chemical Society (ACS)
2 publications, 33.33%
|
|
1
2
|
- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2023,2024],"ids":[0,0],"codes":[0,0],"imageUrls":["",""],"datasets":[{"label":"Citations number","data":[4,2],"backgroundColor":["#3B82F6","#3B82F6"],"percentage":["66.67","33.33"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Journal of Molecular Liquids","Membranes","Crystals","ACS applied materials & interfaces","Industrial & Engineering Chemistry Research"],"ids":[13597,6479,15823,1458,12141],"codes":[0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp"],"datasets":[{"label":"","data":[2,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[33.33,16.67,16.67,16.67,16.67],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Elsevier","Multidisciplinary Digital Publishing Institute (MDPI)","American Chemical Society (ACS)"],"ids":[17,202,40],"codes":[0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp"],"datasets":[{"label":"","data":[2,2,2],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6"],"percentage":[33.33,33.33,33.33],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Khodov I. A. et al. Exploring the Conformational Equilibrium of Mefenamic Acid Released from Silica Aerogels via NMR Analysis // International Journal of Molecular Sciences. 2023. Vol. 24. No. 8. p. 6882.
GOST all authors (up to 50)
Copy
Khodov I. A., Sobornova V. V., Mulloyarova V., Belov K. V., Dyshin A. A., Batista de Carvalho L. A. E., Tolstoy P. M., Kiselev M. Exploring the Conformational Equilibrium of Mefenamic Acid Released from Silica Aerogels via NMR Analysis // International Journal of Molecular Sciences. 2023. Vol. 24. No. 8. p. 6882.
Cite this
RIS
Copy
TY - JOUR
DO - 10.3390/ijms24086882
UR - https://doi.org/10.3390%2Fijms24086882
TI - Exploring the Conformational Equilibrium of Mefenamic Acid Released from Silica Aerogels via NMR Analysis
T2 - International Journal of Molecular Sciences
AU - Khodov, Ilya A.
AU - Sobornova, Valentina V
AU - Mulloyarova, Valeriya
AU - Belov, Konstantin V.
AU - Dyshin, Alexey A.
AU - Batista de Carvalho, Luís A. E.
AU - Tolstoy, Peter M.
AU - Kiselev, Michael
PY - 2023
DA - 2023/04/07 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 6882
IS - 8
VL - 24
PMID - 37108046
SN - 1661-6596
SN - 1422-0067
ER -
Cite this
BibTex
Copy
@article{2023_Khodov,
author = {Ilya A. Khodov and Valentina V Sobornova and Valeriya Mulloyarova and Konstantin V. Belov and Alexey A. Dyshin and Luís A. E. Batista de Carvalho and Peter M. Tolstoy and Michael Kiselev},
title = {Exploring the Conformational Equilibrium of Mefenamic Acid Released from Silica Aerogels via NMR Analysis},
journal = {International Journal of Molecular Sciences},
year = {2023},
volume = {24},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {apr},
url = {https://doi.org/10.3390%2Fijms24086882},
number = {8},
pages = {6882},
doi = {10.3390/ijms24086882}
}
Cite this
MLA
Copy
Khodov, Ilya A., et al. “Exploring the Conformational Equilibrium of Mefenamic Acid Released from Silica Aerogels via NMR Analysis.” International Journal of Molecular Sciences, vol. 24, no. 8, Apr. 2023, p. 6882. https://doi.org/10.3390%2Fijms24086882.