Open Access
A New, Convenient Way to Fully Substituted α,β-Unsaturated γ-Hydroxy Butyrolactams
Igor A Kurenkov
1
,
Alexander V. Leontiev
1
,
Publication type: Journal Article
Publication date: 2023-06-16
scimago Q1
wos Q1
SJR: 1.273
CiteScore: 9.0
Impact factor: 4.9
ISSN: 16616596, 14220067
PubMed ID:
37373361
Catalysis
Organic Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Computer Science Applications
Spectroscopy
Molecular Biology
General Medicine
Abstract
The synthesis of novel, highly functionalized 5-hydroxy 3-pyrrolin-2-ones via a two-step procedure involving an addition reaction between KCN and corresponding chalcones, followed by ring condensation of the obtained β-cyano ketones with het(aryl)aldehydes under basic conditions is described. This protocol enables the preparation of various 3,5-di-aryl/heteroaryl-4-benzyl substituted α,β-unsaturated γ-hydroxy butyrolactams, which are subjects of significant interest to synthetic organic and medicinal chemistry.
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9
Total citations:
9
Citations from 2024:
9
(100%)
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GOST
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Aksenov A. et al. A New, Convenient Way to Fully Substituted α,β-Unsaturated γ-Hydroxy Butyrolactams // International Journal of Molecular Sciences. 2023. Vol. 24. No. 12. p. 10213.
GOST all authors (up to 50)
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Aksenov A., Aksenov D. A., Kurenkov I. A., Leontiev A. V., Aksenov N. A. A New, Convenient Way to Fully Substituted α,β-Unsaturated γ-Hydroxy Butyrolactams // International Journal of Molecular Sciences. 2023. Vol. 24. No. 12. p. 10213.
Cite this
RIS
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TY - JOUR
DO - 10.3390/ijms241210213
UR - https://doi.org/10.3390/ijms241210213
TI - A New, Convenient Way to Fully Substituted α,β-Unsaturated γ-Hydroxy Butyrolactams
T2 - International Journal of Molecular Sciences
AU - Aksenov, Alexander V.
AU - Aksenov, Dmitrii A
AU - Kurenkov, Igor A
AU - Leontiev, Alexander V.
AU - Aksenov, Nicolai A.
PY - 2023
DA - 2023/06/16
PB - MDPI
SP - 10213
IS - 12
VL - 24
PMID - 37373361
SN - 1661-6596
SN - 1422-0067
ER -
Cite this
BibTex (up to 50 authors)
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@article{2023_Aksenov,
author = {Alexander V. Aksenov and Dmitrii A Aksenov and Igor A Kurenkov and Alexander V. Leontiev and Nicolai A. Aksenov},
title = {A New, Convenient Way to Fully Substituted α,β-Unsaturated γ-Hydroxy Butyrolactams},
journal = {International Journal of Molecular Sciences},
year = {2023},
volume = {24},
publisher = {MDPI},
month = {jun},
url = {https://doi.org/10.3390/ijms241210213},
number = {12},
pages = {10213},
doi = {10.3390/ijms241210213}
}
Cite this
MLA
Copy
Aksenov, Alexander V., et al. “A New, Convenient Way to Fully Substituted α,β-Unsaturated γ-Hydroxy Butyrolactams.” International Journal of Molecular Sciences, vol. 24, no. 12, Jun. 2023, p. 10213. https://doi.org/10.3390/ijms241210213.