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Open access
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MolBank
,  volume 2022 ,  issue 4 ,  pages M1515

5-(4-Nitrophenyl)furan-2-carboxylic Acid

Publication type: Journal Article
Publication date: 2022-12-02
MDPI
scimago Q4
wos Q4
SJR: 0.142
CiteScore: 0.9
Impact factor: 0.4
ISSN: 14228599
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract

The ever-evolving research in the field of antitubercular agents has led to the identification of several new potential drug classes. Among them, 5-phenyl-furan-2-carboxylic acids have emerged as innovative potential therapeutics, targeting iron acquisition in mycobacterial species. In our efforts to characterize the molecular interactions between these compounds and their protein target (MbtI from M. tuberculosis) by means of co-crystallization experiments, we unexpectedly obtained the structure of 5-(4-nitrophenyl)furan-2-carboxylic acid (1). Herein, we describe the preparation of the compound and its analysis by 1H NMR, 13C NMR, HRMS, and SC-XRD.

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Mori M. et al. 5-(4-Nitrophenyl)furan-2-carboxylic Acid // MolBank. 2022. Vol. 2022. No. 4. p. M1515.
GOST all authors (up to 50) Copy
Mori M., Tresoldi A., Villa S., Cazzaniga G., Bellinzoni M., Meneghetti F. 5-(4-Nitrophenyl)furan-2-carboxylic Acid // MolBank. 2022. Vol. 2022. No. 4. p. M1515.
RIS |
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RIS Copy
TY - JOUR
DO - 10.3390/m1515
UR - https://doi.org/10.3390/m1515
TI - 5-(4-Nitrophenyl)furan-2-carboxylic Acid
T2 - MolBank
AU - Mori, Matteo
AU - Tresoldi, Andrea
AU - Villa, Stefania
AU - Cazzaniga, Giulia
AU - Bellinzoni, M.
AU - Meneghetti, Fiorella
PY - 2022
DA - 2022/12/02
PB - MDPI
SP - M1515
IS - 4
VL - 2022
SN - 1422-8599
ER -
BibTex |
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BibTex (up to 50 authors) Copy
@article{2022_Mori,
author = {Matteo Mori and Andrea Tresoldi and Stefania Villa and Giulia Cazzaniga and M. Bellinzoni and Fiorella Meneghetti},
title = {5-(4-Nitrophenyl)furan-2-carboxylic Acid},
journal = {MolBank},
year = {2022},
volume = {2022},
publisher = {MDPI},
month = {dec},
url = {https://doi.org/10.3390/m1515},
number = {4},
pages = {M1515},
doi = {10.3390/m1515}
}
MLA
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Mori, Matteo, et al. “5-(4-Nitrophenyl)furan-2-carboxylic Acid.” MolBank, vol. 2022, no. 4, Dec. 2022, p. M1515. https://doi.org/10.3390/m1515.