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Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes
Тип публикации: Journal Article
Дата публикации: 2018-11-17
PubMed ID:
30453635
Organic Chemistry
Drug Discovery
Physical and Theoretical Chemistry
Pharmaceutical Science
Molecular Medicine
Analytical Chemistry
Chemistry (miscellaneous)
Краткое описание
1-(p-Methoxyphenyl)tetrazolyl-substituted 6,7-dimethoxy(6,7-methylenedioxy)-1,2,3,4-tetrahydroisoquinolines formed tetrazolyl-substituted azocines in high yields by using activated alkynes. Unsubstituted at 6,7,8-aromatic fragment 1-tetrazolylisoquinoline interacted in several pathways forming tetrazolyl-substituted azocines, 1-tetrazolyl-1-R-vinylisoquinolines and 3-azaspiro[5.5]undeca-1,7,9-triene.
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Titov A. et al. Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes // Molecules. 2018. Vol. 23. No. 11. p. 3010.
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Titov A., Samavati R., Alexandrova E., Borisova T., Dang Thi T., N'Guyen V., Le T., Varlamov A., Van Der Eycken E., Voskressensky L. Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes // Molecules. 2018. Vol. 23. No. 11. p. 3010.
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TY - JOUR
DO - 10.3390/molecules23113010
UR - https://doi.org/10.3390/molecules23113010
TI - Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes
T2 - Molecules
AU - Titov, Alexander
AU - Samavati, Reza
AU - Alexandrova, Elena
AU - Borisova, Tatiana
AU - Dang Thi, Tuyet
AU - N'Guyen, Van
AU - Le, Tuan
AU - Varlamov, Alexey
AU - Van Der Eycken, Erik
AU - Voskressensky, Leonid
PY - 2018
DA - 2018/11/17
PB - MDPI
SP - 3010
IS - 11
VL - 23
PMID - 30453635
SN - 1420-3049
ER -
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@article{2018_Titov,
author = {Alexander Titov and Reza Samavati and Elena Alexandrova and Tatiana Borisova and Tuyet Dang Thi and Van N'Guyen and Tuan Le and Alexey Varlamov and Erik Van Der Eycken and Leonid Voskressensky},
title = {Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes},
journal = {Molecules},
year = {2018},
volume = {23},
publisher = {MDPI},
month = {nov},
url = {https://doi.org/10.3390/molecules23113010},
number = {11},
pages = {3010},
doi = {10.3390/molecules23113010}
}
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Titov, Alexander, et al. “Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes.” Molecules, vol. 23, no. 11, Nov. 2018, p. 3010. https://doi.org/10.3390/molecules23113010.