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Open access
MDPI
Molecules
,  volume 23 ,  issue 11 ,  pages 3010

Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes

Alexander Titov 1
, 
Reza Samavati 1
, 
Elena Alexandrova 1
, 
Tatiana Borisova 1
, 
Tuyet Dang Thi 2
, 
Van N'Guyen 2, 3
, 
Tuan Le 4
, 
Alexey Varlamov 1
, 
Erik Van Der Eycken 1, 5
, 
Leonid Voskressensky 1
1
 
2
 
3
 
4
 
5
 
Publication type: Journal Article
Publication date: 2018-11-17
MDPI
scimago Q1
wos Q2
SJR: 0.865
CiteScore: 8.6
Impact factor: 4.6
ISSN: 14203049
Organic Chemistry
Drug Discovery
Physical and Theoretical Chemistry
Pharmaceutical Science
Molecular Medicine
Analytical Chemistry
Chemistry (miscellaneous)
Abstract

1-(p-Methoxyphenyl)tetrazolyl-substituted 6,7-dimethoxy(6,7-methylenedioxy)-1,2,3,4-tetrahydroisoquinolines formed tetrazolyl-substituted azocines in high yields by using activated alkynes. Unsubstituted at 6,7,8-aromatic fragment 1-tetrazolylisoquinoline interacted in several pathways forming tetrazolyl-substituted azocines, 1-tetrazolyl-1-R-vinylisoquinolines and 3-azaspiro[5.5]undeca-1,7,9-triene.

Found 
Found 
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GOST Copy
Titov A. et al. Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes // Molecules. 2018. Vol. 23. No. 11. p. 3010.
GOST all authors (up to 50) Copy
Titov A., Samavati R., Alexandrova E., Borisova T., Dang Thi T., N'Guyen V., Le T., Varlamov A., Van Der Eycken E., Voskressensky L. Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes // Molecules. 2018. Vol. 23. No. 11. p. 3010.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.3390/molecules23113010
UR - https://doi.org/10.3390/molecules23113010
TI - Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes
T2 - Molecules
AU - Titov, Alexander
AU - Samavati, Reza
AU - Alexandrova, Elena
AU - Borisova, Tatiana
AU - Dang Thi, Tuyet
AU - N'Guyen, Van
AU - Le, Tuan
AU - Varlamov, Alexey
AU - Van Der Eycken, Erik
AU - Voskressensky, Leonid
PY - 2018
DA - 2018/11/17
PB - MDPI
SP - 3010
IS - 11
VL - 23
PMID - 30453635
SN - 1420-3049
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2018_Titov,
author = {Alexander Titov and Reza Samavati and Elena Alexandrova and Tatiana Borisova and Tuyet Dang Thi and Van N'Guyen and Tuan Le and Alexey Varlamov and Erik Van Der Eycken and Leonid Voskressensky},
title = {Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes},
journal = {Molecules},
year = {2018},
volume = {23},
publisher = {MDPI},
month = {nov},
url = {https://doi.org/10.3390/molecules23113010},
number = {11},
pages = {3010},
doi = {10.3390/molecules23113010}
}
MLA
Cite this
MLA Copy
Titov, Alexander, et al. “Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes.” Molecules, vol. 23, no. 11, Nov. 2018, p. 3010. https://doi.org/10.3390/molecules23113010.