Open Access
Open access
Molecules, volume 25, issue 19, pages 4541

Spectroscopic and In Vitro Investigations of Boron(III) Complex with Meso-4-Methoxycarbonylpropylsubstituted Dipyrromethene for Fluorescence Bioimaging Applications

Antina Elena 1
Lisovskaya Svetlana 2, 3
Pavelyev Roman 4
Lodochnikova Olga 4, 5
Islamov Daut 4, 5
Nikitina Liliya 2, 4
Publication typeJournal Article
Publication date2020-10-03
Journal: Molecules
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor4.6
ISSN14203049
Organic Chemistry
Drug Discovery
Physical and Theoretical Chemistry
Pharmaceutical Science
Molecular Medicine
Analytical Chemistry
Chemistry (miscellaneous)
Abstract
This study focuses on the behavior of a new fluorescent marker for labeling individual biomolecules and staining cell organelles developed on a meso-substituted BODIPY platform. Boron(III) complex with meso-4-methoxycarbonylpropylsubstituted 3,3’,5,5’-tetramethyl-2,2′-dipyrromethene has been synthesized and identified via visible, UV-, NMR- and MS-spectra X-ray. The behavior of fluorophore in solutions has been studied with various experimental techniques. It has been found that luminophore exhibits a high quantum yield (almost ~100–75%) in the blue-green region (513–520 nm) and has high photostability. In addition, biological analysis indicates that the fluorophore exhibits a tendency to effectively penetrate into cell membranes. On the other hand, the proposed BODIPY can be used to study the significant differences among a large number of pathogens of mycotic infections, as well as to visualize structural changes in the plasma membrane, which is necessary for the clearance of mammalian cells undergoing apoptotic cell death.

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GOST Copy
Guseva G. et al. Spectroscopic and In Vitro Investigations of Boron(III) Complex with Meso-4-Methoxycarbonylpropylsubstituted Dipyrromethene for Fluorescence Bioimaging Applications // Molecules. 2020. Vol. 25. No. 19. p. 4541.
GOST all authors (up to 50) Copy
Guseva G., Antina E., Berezin M., Lisovskaya S., Pavelyev R., Kayumov A. R., Lodochnikova O., Islamov D., Усачев К., Boichuk S., Nikitina L. Spectroscopic and In Vitro Investigations of Boron(III) Complex with Meso-4-Methoxycarbonylpropylsubstituted Dipyrromethene for Fluorescence Bioimaging Applications // Molecules. 2020. Vol. 25. No. 19. p. 4541.
RIS |
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RIS Copy
TY - JOUR
DO - 10.3390/molecules25194541
UR - https://doi.org/10.3390%2Fmolecules25194541
TI - Spectroscopic and In Vitro Investigations of Boron(III) Complex with Meso-4-Methoxycarbonylpropylsubstituted Dipyrromethene for Fluorescence Bioimaging Applications
T2 - Molecules
AU - Guseva, Galina
AU - Antina, Elena
AU - Berezin, Mikhail
AU - Lisovskaya, Svetlana
AU - Pavelyev, Roman
AU - Lodochnikova, Olga
AU - Islamov, Daut
AU - Nikitina, Liliya
AU - Kayumov, Airat R.
AU - Усачев, К.
AU - Boichuk, Sergei
PY - 2020
DA - 2020/10/03 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 4541
IS - 19
VL - 25
PMID - 33023057
SN - 1420-3049
ER -
BibTex |
Cite this
BibTex Copy
@article{2020_Guseva,
author = {Galina Guseva and Elena Antina and Mikhail Berezin and Svetlana Lisovskaya and Roman Pavelyev and Olga Lodochnikova and Daut Islamov and Liliya Nikitina and Airat R. Kayumov and К. Усачев and Sergei Boichuk},
title = {Spectroscopic and In Vitro Investigations of Boron(III) Complex with Meso-4-Methoxycarbonylpropylsubstituted Dipyrromethene for Fluorescence Bioimaging Applications},
journal = {Molecules},
year = {2020},
volume = {25},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {oct},
url = {https://doi.org/10.3390%2Fmolecules25194541},
number = {19},
pages = {4541},
doi = {10.3390/molecules25194541}
}
MLA
Cite this
MLA Copy
Guseva, Galina, et al. “Spectroscopic and In Vitro Investigations of Boron(III) Complex with Meso-4-Methoxycarbonylpropylsubstituted Dipyrromethene for Fluorescence Bioimaging Applications.” Molecules, vol. 25, no. 19, Oct. 2020, p. 4541. https://doi.org/10.3390%2Fmolecules25194541.
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