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Direct Conversion of 3-(2-Nitroethyl)-1H-Indoles into 2-(1H-Indol-2-yl)Acetonitriles

Тип публикацииJournal Article
Дата публикации2021-10-11
scimago Q1
wos Q2
БС1
SJR0.865
CiteScore8.6
Impact factor4.6
ISSN14203049
Organic Chemistry
Drug Discovery
Physical and Theoretical Chemistry
Pharmaceutical Science
Molecular Medicine
Analytical Chemistry
Chemistry (miscellaneous)
Краткое описание

The recently discovered [4+1]-spirocyclization of nitroalkenes to indoles provided a convenient new approach to 2-(1H-indol-2-yl)acetonitriles. However, this reaction was complicated by the formation of inert 3-(2-nitroethyl)-1H-indole byproducts. Herein, we offer a workaround this problem that allows for effective transformation of the unwanted byproducts into acetonitrile target molecules.

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International Journal of Molecular Sciences
1 публикация, 9.09%
Molecules
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Journal of Organic Chemistry
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Synthesis
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Russian Chemical Reviews
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ACS Omega
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Russian Journal of Organic Chemistry
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Журнал органической химии
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Asian Journal of Organic Chemistry
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Russian Chemical Bulletin
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Russian Journal of General Chemistry
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ГОСТ |
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Aksenov A. et al. Direct Conversion of 3-(2-Nitroethyl)-1H-Indoles into 2-(1H-Indol-2-yl)Acetonitriles // Molecules. 2021. Vol. 26. No. 20. p. 6132.
ГОСТ со всеми авторами (до 50) Скопировать
Aksenov A., Aksenov N. A., Aleksandrova E. V., Aksenov D. A., Grishin I. Yu., Sorokina E. A., Wenger A., Rubin M. Direct Conversion of 3-(2-Nitroethyl)-1H-Indoles into 2-(1H-Indol-2-yl)Acetonitriles // Molecules. 2021. Vol. 26. No. 20. p. 6132.
RIS |
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TY - JOUR
DO - 10.3390/molecules26206132
UR - https://doi.org/10.3390/molecules26206132
TI - Direct Conversion of 3-(2-Nitroethyl)-1H-Indoles into 2-(1H-Indol-2-yl)Acetonitriles
T2 - Molecules
AU - Aksenov, Alexander V.
AU - Aksenov, Nicolai A.
AU - Aleksandrova, Elena V
AU - Aksenov, Dmitrii A
AU - Grishin, Igor Yu
AU - Sorokina, Elena A
AU - Wenger, Allison
AU - Rubin, Michael
PY - 2021
DA - 2021/10/11
PB - MDPI
SP - 6132
IS - 20
VL - 26
PMID - 34684712
SN - 1420-3049
ER -
BibTex |
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BibTex (до 50 авторов) Скопировать
@article{2021_Aksenov,
author = {Alexander V. Aksenov and Nicolai A. Aksenov and Elena V Aleksandrova and Dmitrii A Aksenov and Igor Yu Grishin and Elena A Sorokina and Allison Wenger and Michael Rubin},
title = {Direct Conversion of 3-(2-Nitroethyl)-1H-Indoles into 2-(1H-Indol-2-yl)Acetonitriles},
journal = {Molecules},
year = {2021},
volume = {26},
publisher = {MDPI},
month = {oct},
url = {https://doi.org/10.3390/molecules26206132},
number = {20},
pages = {6132},
doi = {10.3390/molecules26206132}
}
MLA
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Aksenov, Alexander V., et al. “Direct Conversion of 3-(2-Nitroethyl)-1H-Indoles into 2-(1H-Indol-2-yl)Acetonitriles.” Molecules, vol. 26, no. 20, Oct. 2021, p. 6132. https://doi.org/10.3390/molecules26206132.