Open Access
Open access
Molecules, том 27, издание 4, номер публикации: 1396

BODIPY Conjugates as Functional Compounds for Medical Diagnostics and Treatment

Тип документаJournal Article
Дата публикации2022-02-18
ИздательMultidisciplinary Digital Publishing Institute (MDPI)
Название журналаMolecules
Квартиль по SCImagoQ1
Квартиль по Web of ScienceQ2
Импакт-фактор 20214.93
ISSN14203049
Organic Chemistry
Drug Discovery
Physical and Theoretical Chemistry
Pharmaceutical Science
Molecular Medicine
Analytical Chemistry
Chemistry (miscellaneous)
Краткое описание
Fluorescent dyes absorbing and emitting in the visible and near-IR regions are promising for the development of fluorescent probes for labeling and bio-visualization of body cells. The ability to absorb and emit in the long-wavelength region increases the efficiency of recording the spectral signals of the probes due to the higher permeability of the skin layers. Compared to other fluorescent dyes, BODIPYs are attractive due to their excellent photophysical properties–narrow absorption and emission, intense fluorescence, simple signal modulation for the practical applications. As part of conjugates with biomolecules, BODIPY could act as a biomarker, but as therapeutic agent, which allows solving several problems at once-labeling or bioimaging and treatment based on the suppression of pathogenic microflora and cancer cells, which provides a huge potential for practical application of BODIPY conjugates in medicine. The review is devoted to the discussion of the recent, promising directions of BODIPY application in the field of conjugation with biomolecules. The first direction is associated with the development of BODIPY conjugates with drugs, including compounds of platinum, paclitaxel, chlorambucil, isoxazole, capsaicin, etc. The second direction is devoted to the labeling of vitamins, hormones, lipids, and other biomolecules to control the processes of their transport, localization in target cells, and metabolism. Within the framework of the third direction, the problem of obtaining functional optically active materials by conjugating BODIPY with other colored and fluorescent particles, in particular, phthalocyanines, is being solved.
Пристатейные ссылки: 73
Цитируется в публикациях: 11
Design, Spectral Characteristics, and Possibilities for Practical Application of BODIPY FL-Labeled Monoterpenoid
Guseva G.B., Antina E.V., Berezin M.B., Pavelyev R.S., Kayumov A.R., Ostolopovskaya O.V., Gilfanov I.R., Frolova L.L., Kutchin A.V., Akhverdiev R.F., Lisovskaya S.A., Trizna E.Y., Lodochnikova O.A., Islamov D.R., Efimov S.V., et. al.
Q1 ACS Applied Bio Materials 2021 цитирований: 6
Photoactivatable prodrug for simultaneous release of mertansine and CO along with a BODIPY derivative as a luminescent marker in mitochondria: a proof of concept for NIR image-guided cancer therapy
Tiwari R., Shinde P.S., Sreedharan S., Dey A.K., Vallis K.A., Mhaske S.B., Pramanik S.K., Das A.
Q1 Chemical Science 2021 цитирований: 10
Open Access
Open access
BODIPY-based monofunctional Pt (II) complexes for specific photocytotoxicity against cancer cells.
Qi F., Yuan H., Chen Y., Guo Y., Zhang S., Liu Z., He W., Guo Z.
Q1 Journal of Inorganic Biochemistry 2021 цитирований: 5
Combining cross-coupling reaction and Knoevenagel condensation in the synthesis of glyco-BODIPY probes for DC-SIGN super-resolution bioimaging.
Biagiotti G., Purić E., Urbančič I., Krišelj A., Weiss M., Mravljak J., Gellini C., Lay L., Chiodo F., Anderluh M., Cicchi S., Richichi B.
Q1 Bioorganic Chemistry 2021 цитирований: 4
Maloplatin-B, a Cisplatin-Based BODIPY-Tagged Mito-Specific "Chemo-PDT" Agent Active in Red Light.
Ramu V., Kundu P., Kondaiah P., Chakravarty A.R.
Q1 Inorganic Chemistry 2021 цитирований: 8
Lysosome Specific Platinum(II) Catecholates with Photoactive BODIPY for Imaging and Photodynamic Therapy in Near‐IR Light
Ramu V., Kundu P., Upadhyay A., Kondaiah P., Chakravarty A.R.
Q2 European Journal of Inorganic Chemistry 2021 цитирований: 5
Monitoring the formation of insulin oligomers using a NIR emitting glucose-conjugated BODIPY dye.
Mora A.K., Murudkar S., Shivran N., Mula S., Chattopadhyay S., Nath S.
Q1 International Journal of Biological Macromolecules 2021 цитирований: 6
Nanomaterial‐mediated platinum drug‐based combinatorial cancer therapy
Deng Z., Wang N., Ai F., Wang Z., Zhu G.
View 2020 цитирований: 8
Cu-catalyzed click conjugation of cobalamin to a BODIPY-based fluorophore: A versatile tool to explore the cellular biology of vitamin B12.
Haghdoost M.M., Sauvageau E., Oguadinma P., Tran H., Lefrancois S., Castonguay A.
Q1 Journal of Inorganic Biochemistry 2020 цитирований: 1
BODI-Pt, a Green-Light-Activatable and Carboplatin-Based Platinum(IV) Anticancer Prodrug with Enhanced Activation and Cytotoxicity.
Yao H., Chen S., Deng Z., Tse M., Matsuda Y., Zhu G.
Q1 Inorganic Chemistry 2020 цитирований: 24
Design, synthesis and cytotoxicity of BODIPY FL labelled triterpenoids
Brandes B., Hoenke S., Fischer L., Csuk R.
Q1 European Journal of Medicinal Chemistry 2020 цитирований: 14
Purple silicon(IV) phthalocyanine axially substituted with BODIPY groups
Kaya E.N., Köksoy B., Yeşilot S., Durmuş M.
Q1 Dyes and Pigments 2020 цитирований: 8
Ruthenium(II) Conjugates of Boron-Dipyrromethene and Biotin for Targeted Photodynamic Therapy in Red Light.
Paul S., Kundu P., Bhattacharyya U., Garai A., Maji R.C., Kondaiah P., Chakravarty A.R.
Q1 Inorganic Chemistry 2019 цитирований: 21
Stable J-aggregation of an aza-BODIPY-lipid in a liposome for optical cancer imaging.
Cheng M.H., Harmatys K.M., Charron D.M., Chen J., Zheng G.
Q1 Angewandte Chemie - International Edition 2019 цитирований: 77
Self-assembly of photosensitive and chemotherapeutic drugs for combined photodynamic-chemo cancer therapy with real-time tracing property
Wang S., Li J., Ye Z., Li J., Wang A., Hu J., Bai S., Yin J.
Q2 Colloids and Surfaces A: Physicochemical and Engineering Aspects 2019 цитирований: 18
Метрики

Поделиться

Цитировать
ГОСТ |
Цитировать
1. Antina E. и др. BODIPY Conjugates as Functional Compounds for Medical Diagnostics and Treatment // Molecules. 2022. Т. 27. № 4. С. 1396.
RIS |
Цитировать

TY - JOUR

DO - 10.3390/molecules27041396

UR - http://dx.doi.org/10.3390/molecules27041396

TI - BODIPY Conjugates as Functional Compounds for Medical Diagnostics and Treatment

T2 - Molecules

AU - Antina, Elena

AU - Bumagina, Natalia

AU - Marfin, Yuriy

AU - Guseva, Galina

AU - Nikitina, Liliya

AU - Sbytov, Dmitry

AU - Telegin, Felix

PY - 2022

DA - 2022/02/18

PB - MDPI AG

SP - 1396

IS - 4

VL - 27

SN - 1420-3049

ER -

BibTex |
Цитировать

@article{Antina_2022,

doi = {10.3390/molecules27041396},

url = {https://doi.org/10.3390%2Fmolecules27041396},

year = 2022,

month = {feb},

publisher = {{MDPI} {AG}},

volume = {27},

number = {4},

pages = {1396},

author = {Elena Antina and Natalia Bumagina and Yuriy Marfin and Galina Guseva and Liliya Nikitina and Dmitry Sbytov and Felix Telegin},

title = {{BODIPY} Conjugates as Functional Compounds for Medical Diagnostics and Treatment},

journal = {Molecules}

}

MLA
Цитировать
Antina, Elena, et al. “BODIPY Conjugates as Functional Compounds for Medical Diagnostics and Treatment.” Molecules, vol. 27, no. 4, Feb. 2022, p. 1396. Crossref, https://doi.org/10.3390/molecules27041396.