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Open access
MDPI
Molecules
,  volume 27 ,  issue 9 ,  pages 2808

One-Pot Synthesis of (E)-2-(3-Oxoindolin-2-ylidene)-2-arylacetonitriles

Publication type: Journal Article
Publication date: 2022-04-28
MDPI
scimago Q1
wos Q2
SJR: 0.865
CiteScore: 8.6
Impact factor: 4.6
ISSN: 14203049
Organic Chemistry
Drug Discovery
Physical and Theoretical Chemistry
Pharmaceutical Science
Molecular Medicine
Analytical Chemistry
Chemistry (miscellaneous)
Abstract

A highly efficient and expeditious one-pot approach towards 2-(3-oxoindolin-2-yl)acetonitriles was designed, which involves a base-assisted aldol reaction of ortho-nitroacetophenones, followed by hydrocyanation, triggering an unusual reductive cyclization reaction.

Found 
Found 
5 citations
Aksenov Aleksandr
🥼 🤝
DSc in Chemistry, professor
243 publications,  2 187 citations,  15 reviews
h-index: 24
North Caucasus Federal University
North Caucasus Federal University
Research interests
Medicinal Chemistry
Organic Chemistry
2 citations
Sosnovskikh Vyacheslav
DSc in Chemistry, professor
355 publications,  4 721 citations
h-index: 30
Ural Federal University
Ural Federal University
1 citation
Beloglazkina Elena
DSc in Chemistry, professor
296 publications,  3 248 citations,  11 reviews
h-index: 29
Lomonosov Moscow State University
Lomonosov Moscow State University
1 citation
Gorbunova Yuliya
DSc in Chemistry, professor, full member of the Russian Academy of Sciences 
284 publications,  4 398 citations,  65 reviews
h-index: 34
Lomonosov Moscow State University
Lomonosov Moscow State University
Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences
Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences
A.N. Frumkin Institute of Physical Chemistry and Electrochemistry of the Russian Academy of Sciences
A.N. Frumkin Institute of Physical Chemistry and Electrochemistry of the Russian Academy of Sciences
Research interests
Coordination Chemistry
Lanthanides
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Tetrapyrrolic compounds
1 citation
Volcho Konstantin
DSc in Chemistry, professor of the Russian Academy of Sciences 
279 publications,  3 898 citations,  65 reviews
h-index: 31
N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the Siberian Branch of the Russian Academy of Sciences
N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the Siberian Branch of the Russian Academy of Sciences
1 citation
Danilkina Natalia
44 publications,  625 citations
h-index: 14
Saint Petersburg State University
Saint Petersburg State University
Research interests
Bioorganic chemistry
Click chemistry
Heterocyclic compounds
Medicinal Chemistry
Organic Chemistry
1 citation
Osipov Sergey
DSc in Chemistry
138 publications,  2 739 citations,  3 reviews
h-index: 29
A.N.Nesmeyanov Institute of Organoelement Compounds of the Russian Academy of Sciences
A.N.Nesmeyanov Institute of Organoelement Compounds of the Russian Academy of Sciences
1 citation
Gazizov Almir
🥼
DSc in Chemistry
157 publications,  889 citations,  23 reviews
h-index: 14
A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
Research interests
Heterocyclic compounds
Organic Chemistry
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Karasik Andrey
DSc in Chemistry, professor, associate member of the Russian Academy of Sciences 
224 publications,  2 599 citations
h-index: 26
A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
Research interests
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Luminescence
Phosphorus ligands
1 citation
Dotsenko Viktor
DSc in Chemistry, professor
244 publications,  2 741 citations,  2 reviews
h-index: 22
North Caucasus Federal University
North Caucasus Federal University
Kuban State University
Kuban State University
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Active methylene compounds
Biological activity
Heterocyclic compounds
Malononitrile
Selenoamides
Thioamides
1 citation
Zagidullin Almaz
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PhD in Chemistry
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h-index: 17
A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
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Research interests
Asymmetric metal complex catalysis
Chemistry of organic and organoelement compounds; chemistry of polymers; production of materials
Coordination chemistry of phosphorus
Organoelement chemistry
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1 citation
Arutiunov Nikolai
PhD in Chemistry, senior lecturer
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h-index: 9
North Caucasus Federal University
North Caucasus Federal University
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Ilkin Vladimir
PhD in Chemistry
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h-index: 7
Ural Federal University
Ural Federal University
Research interests
Catalysis
Heterocyclic compounds
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Ivleva Elena
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Samara State Technical University
Samara State Technical University
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1 citation
Kurenkov Igor
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h-index: 7
North Caucasus Federal University
North Caucasus Federal University
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Organic Chemistry
Synthesis
1 citation
Krylov Igor
PhD in Chemistry
78 publications,  1 885 citations,  18 reviews
h-index: 25
N.D. Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences
N.D. Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences
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Plant protection
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Tikhomirov Alexander
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DSc in Chemistry, associate professor
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Mendeleev University of Chemical Technology of Russia
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Gause Institute of New Antibiotics
Gause Institute of New Antibiotics
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1 citation
Ivanov Andrey
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h-index: 12
A.E. Favorsky Irkutsk Institute of Chemistry of the Siberian Branch of the Russian Academy of Sciences
A.E. Favorsky Irkutsk Institute of Chemistry of the Siberian Branch of the Russian Academy of Sciences
1 citation
Buev Evgeny
PhD in Chemistry
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Ural Federal University
Ural Federal University
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GOST |
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GOST Copy
Aksenov N. A. et al. One-Pot Synthesis of (E)-2-(3-Oxoindolin-2-ylidene)-2-arylacetonitriles // Molecules. 2022. Vol. 27. No. 9. p. 2808.
GOST all authors (up to 50) Copy
Aksenov N. A., Aksenov A. V., Kurenkov I. A., Kirillov N. K., Aksenov D. A., Arutiunov N. A., Aksenova D. S., Rubin M. One-Pot Synthesis of (E)-2-(3-Oxoindolin-2-ylidene)-2-arylacetonitriles // Molecules. 2022. Vol. 27. No. 9. p. 2808.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.3390/molecules27092808
UR - https://doi.org/10.3390/molecules27092808
TI - One-Pot Synthesis of (E)-2-(3-Oxoindolin-2-ylidene)-2-arylacetonitriles
T2 - Molecules
AU - Aksenov, Nicolai A.
AU - Aksenov, Alexander V
AU - Kurenkov, Igor A
AU - Kirillov, Nikita K
AU - Aksenov, Dmitrii A
AU - Arutiunov, Nikolai A
AU - Aksenova, Daria S
AU - Rubin, Michael
PY - 2022
DA - 2022/04/28
PB - MDPI
SP - 2808
IS - 9
VL - 27
PMID - 35566159
SN - 1420-3049
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2022_Aksenov,
author = {Nicolai A. Aksenov and Alexander V Aksenov and Igor A Kurenkov and Nikita K Kirillov and Dmitrii A Aksenov and Nikolai A Arutiunov and Daria S Aksenova and Michael Rubin},
title = {One-Pot Synthesis of (E)-2-(3-Oxoindolin-2-ylidene)-2-arylacetonitriles},
journal = {Molecules},
year = {2022},
volume = {27},
publisher = {MDPI},
month = {apr},
url = {https://doi.org/10.3390/molecules27092808},
number = {9},
pages = {2808},
doi = {10.3390/molecules27092808}
}
MLA
Cite this
MLA Copy
Aksenov, Nicolai A., et al. “One-Pot Synthesis of (E)-2-(3-Oxoindolin-2-ylidene)-2-arylacetonitriles.” Molecules, vol. 27, no. 9, Apr. 2022, p. 2808. https://doi.org/10.3390/molecules27092808.