Open Access
Open access
MDPI
Molecules
,  volume 27 ,  issue 15 ,  pages 4761

Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles

Publication type: Journal Article
Publication date: 2022-07-25
MDPI
scimago Q1
wos Q2
SJR: 0.865
CiteScore: 8.6
Impact factor: 4.6
ISSN: 14203049
Organic Chemistry
Drug Discovery
Physical and Theoretical Chemistry
Pharmaceutical Science
Molecular Medicine
Analytical Chemistry
Chemistry (miscellaneous)
Abstract

A set of heterocyclic products was synthesized from natural (+)-camphor and semi-synthetic (−)-camphor. Then, 2-Imino-4-thiazolidinones and 2,3-dihydrothiazoles were obtained using a three-step procedure. For the synthesized compounds, their antiviral activity against the vaccinia virus and Marburg virus was studied. New promising agents active against both viruses were found among the tested compounds.

Found 
Found 
4 citations
Yarovaya Olga
PhD in Chemistry
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N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the Siberian Branch of the Russian Academy of Sciences
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Danilkina Natalia
44 publications,  625 citations
h-index: 14
Saint Petersburg State University
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Research interests
Bioorganic chemistry
Click chemistry
Heterocyclic compounds
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Osipov Sergey
DSc in Chemistry
138 publications,  2 739 citations,  3 reviews
h-index: 29
A.N.Nesmeyanov Institute of Organoelement Compounds of the Russian Academy of Sciences
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Gazizov Almir
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157 publications,  889 citations,  23 reviews
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A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
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Organic Chemistry
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Biological activity
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Asymmetric metal complex catalysis
Chemistry of organic and organoelement compounds; chemistry of polymers; production of materials
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Aksenov Aleksandr
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Computer simulation
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Molecular docking
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Ilkin Vladimir
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Ural Federal University
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GOST |
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GOST Copy
Oreshko V. V. et al. Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles // Molecules. 2022. Vol. 27. No. 15. p. 4761.
GOST all authors (up to 50) Copy
Oreshko V. V., Kovaleva K., Mordvinova E. D., Yarovaya O. I., Gatilov Y. V., Shcherbakov D. N., Bormotov N. I., Serova O. A., Shishkina L. N., Salakhutdinov N. F. Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles // Molecules. 2022. Vol. 27. No. 15. p. 4761.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.3390/molecules27154761
UR - https://doi.org/10.3390/molecules27154761
TI - Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles
T2 - Molecules
AU - Oreshko, Vladislav V
AU - Kovaleva, Kseniya
AU - Mordvinova, Ekaterina D.
AU - Yarovaya, Olga I.
AU - Gatilov, Yuri V.
AU - Shcherbakov, Dmitriy N.
AU - Bormotov, Nikolai I.
AU - Serova, Olga A.
AU - Shishkina, Larisa N
AU - Salakhutdinov, Nariman F.
PY - 2022
DA - 2022/07/25
PB - MDPI
SP - 4761
IS - 15
VL - 27
PMID - 35897931
SN - 1420-3049
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2022_Oreshko,
author = {Vladislav V Oreshko and Kseniya Kovaleva and Ekaterina D. Mordvinova and Olga I. Yarovaya and Yuri V. Gatilov and Dmitriy N. Shcherbakov and Nikolai I. Bormotov and Olga A. Serova and Larisa N Shishkina and Nariman F. Salakhutdinov},
title = {Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles},
journal = {Molecules},
year = {2022},
volume = {27},
publisher = {MDPI},
month = {jul},
url = {https://doi.org/10.3390/molecules27154761},
number = {15},
pages = {4761},
doi = {10.3390/molecules27154761}
}
MLA
Cite this
MLA Copy
Oreshko, Vladislav V., et al. “Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles.” Molecules, vol. 27, no. 15, Jul. 2022, p. 4761. https://doi.org/10.3390/molecules27154761.