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Enantioselective, Decarboxylative (3+2)-Cycloaddition of Azomethine Ylides and Chromone-3-Carboxylic Acids
Publication type: Journal Article
Publication date: 2022-10-11
PubMed ID:
36296402
Organic Chemistry
Drug Discovery
Physical and Theoretical Chemistry
Pharmaceutical Science
Molecular Medicine
Analytical Chemistry
Chemistry (miscellaneous)
Abstract
Herein, we describe the synthesis of a variety of chiral hybrid pyrrolidine-chromanone polycyclic derivatives. A convenient (3+2)-annulation of azomethine ylides with chromone-3-carboxylic acid realized under Brønsted base catalysis produced highly functionalized products in high yields with good stereoselectivities through asymmetric, intermolecular, and decarboxylative (3+2)-cyclization.
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Kowalska E., Sieron L., Albrecht A. Enantioselective, Decarboxylative (3+2)-Cycloaddition of Azomethine Ylides and Chromone-3-Carboxylic Acids // Molecules. 2022. Vol. 27. No. 20. p. 6809.
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Kowalska E., Sieron L., Albrecht A. Enantioselective, Decarboxylative (3+2)-Cycloaddition of Azomethine Ylides and Chromone-3-Carboxylic Acids // Molecules. 2022. Vol. 27. No. 20. p. 6809.
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TY - JOUR
DO - 10.3390/molecules27206809
UR - https://doi.org/10.3390/molecules27206809
TI - Enantioselective, Decarboxylative (3+2)-Cycloaddition of Azomethine Ylides and Chromone-3-Carboxylic Acids
T2 - Molecules
AU - Kowalska, Ewelina
AU - Sieron, Leslaw
AU - Albrecht, Anna
PY - 2022
DA - 2022/10/11
PB - MDPI
SP - 6809
IS - 20
VL - 27
PMID - 36296402
SN - 1420-3049
ER -
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@article{2022_Kowalska,
author = {Ewelina Kowalska and Leslaw Sieron and Anna Albrecht},
title = {Enantioselective, Decarboxylative (3+2)-Cycloaddition of Azomethine Ylides and Chromone-3-Carboxylic Acids},
journal = {Molecules},
year = {2022},
volume = {27},
publisher = {MDPI},
month = {oct},
url = {https://doi.org/10.3390/molecules27206809},
number = {20},
pages = {6809},
doi = {10.3390/molecules27206809}
}
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MLA
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Kowalska, Ewelina, et al. “Enantioselective, Decarboxylative (3+2)-Cycloaddition of Azomethine Ylides and Chromone-3-Carboxylic Acids.” Molecules, vol. 27, no. 20, Oct. 2022, p. 6809. https://doi.org/10.3390/molecules27206809.