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MDPI
Nanomaterials
,  volume 12 ,  issue 1 ,  pages 16

Evaluation of the Safety and Toxicity of the Original Copper Nanocomposite Based on Poly-N-vinylimidazole

Irina A Shurygina 1
, 
Galina F Prozorova 2
, 
Irina S Trukhan 1
, 
Svetlana A Korzhova 2
, 
Nataliya N Dremina 1
, 
Artem M. Emel’yanov 2
, 
Olesya V Say 1
, 
Nadezhda P Kuznetsova 2
, 
Alexander S. Pozdnyakov 2
, 
Michael G Shurygin 1
1
 
Irkutsk Scientific Center of Surgery and Traumatology, 1 Bortsov Revolutsii Street, 664003 Irkutsk, Russia | 
2
 
Publication type: Journal Article
Publication date: 2021-12-22
MDPI
scimago Q1
wos Q2
SJR: 0.811
CiteScore: 9.2
Impact factor: 4.3
ISSN: 20794991
DOI:  10.3390/nano12010016
PubMed ID:  35009966
General Chemical Engineering
General Materials Science
Abstract

A new original copper nanocomposite based on poly-N-vinylimidazole was synthesized and characterized by a complex of modern physicochemical and biological methods. The low cytotoxicity of the copper nanocomposite in relation to the cultured hepatocyte cells was found. The possibility to involve the copper from the nanocomposite in the functioning of the copper-dependent enzyme systems was evaluated during the incubation of the hepatocyte culture with this nanocomposite introduced to the nutrient medium. The synthesized new water-soluble copper-containing nanocomposite is promising for biotechnological and biomedical research as a new non-toxic hydrophilic preparation that is allowed to regulate the work of key enzymes involved in energy metabolism and antioxidant protection as well as potentially serving as an additional source of copper.

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GOST |
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GOST Copy
Shurygina I. A. et al. Evaluation of the Safety and Toxicity of the Original Copper Nanocomposite Based on Poly-N-vinylimidazole // Nanomaterials. 2021. Vol. 12. No. 1. p. 16.
GOST all authors (up to 50) Copy
Shurygina I. A., Prozorova G. F., Trukhan I. S., Korzhova S. A., Dremina N. N., Emel’yanov A. M., Say O. V., Kuznetsova N. P., Pozdnyakov A. S., Shurygin M. G. Evaluation of the Safety and Toxicity of the Original Copper Nanocomposite Based on Poly-N-vinylimidazole // Nanomaterials. 2021. Vol. 12. No. 1. p. 16.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.3390/nano12010016
UR - https://doi.org/10.3390/nano12010016
TI - Evaluation of the Safety and Toxicity of the Original Copper Nanocomposite Based on Poly-N-vinylimidazole
T2 - Nanomaterials
AU - Shurygina, Irina A
AU - Prozorova, Galina F
AU - Trukhan, Irina S
AU - Korzhova, Svetlana A
AU - Dremina, Nataliya N
AU - Emel’yanov, Artem M.
AU - Say, Olesya V
AU - Kuznetsova, Nadezhda P
AU - Pozdnyakov, Alexander S.
AU - Shurygin, Michael G
PY - 2021
DA - 2021/12/22
PB - MDPI
SP - 16
IS - 1
VL - 12
PMID - 35009966
SN - 2079-4991
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2021_Shurygina,
author = {Irina A Shurygina and Galina F Prozorova and Irina S Trukhan and Svetlana A Korzhova and Nataliya N Dremina and Artem M. Emel’yanov and Olesya V Say and Nadezhda P Kuznetsova and Alexander S. Pozdnyakov and Michael G Shurygin},
title = {Evaluation of the Safety and Toxicity of the Original Copper Nanocomposite Based on Poly-N-vinylimidazole},
journal = {Nanomaterials},
year = {2021},
volume = {12},
publisher = {MDPI},
month = {dec},
url = {https://doi.org/10.3390/nano12010016},
number = {1},
pages = {16},
doi = {10.3390/nano12010016}
}
MLA
Cite this
MLA Copy
Shurygina, Irina A., et al. “Evaluation of the Safety and Toxicity of the Original Copper Nanocomposite Based on Poly-N-vinylimidazole.” Nanomaterials, vol. 12, no. 1, Dec. 2021, p. 16. https://doi.org/10.3390/nano12010016.