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Nanomaterials, volume 13, issue 14, pages 2128

Antifungal Effect of Polymethyl Methacrylate Resin Base with Embedded Au Nanoparticles

Ivan Marić 1, 2
Anamarija Zore 1
Franc Rojko 1
A.S. Škapin 3, 4
Roman Štukelj 1
Aleksander Učakar 5
Rajko Vidrih 6
Valentina Veselinović 7
Marijan Gotić 2
Klemen Bohinc 1
1
 
Faculty of Health Sciences, University of Ljubljana, 1000 Ljubljana, Slovenia
2
 
Ruđer Bošković Institute, 10000 Zagreb, Croatia
3
 
Slovenian National Building and Civil Engineering Institute, 1000 Ljubljana, Slovenia
4
 
Faculty of Polymer Technology-FTPO, Ozare 19, 2380 Slovenj Gradec, Slovenia
5
 
Institute Jožef Stefan, Jamova cesta 39, 1000 Ljubljana, Slovenia
6
 
Biotechnical Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia
7
 
Faculty of Medicine, University of Banja Luka, 78000 Banja Luka, Bosnia and Herzegovina
Publication typeJournal Article
Publication date2023-07-22
Journal: Nanomaterials
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor5.3
ISSN20794991
General Chemical Engineering
General Materials Science
Abstract

Full and partial restorations in dentistry must replicate the characteristics of the patient’s natural teeth. Materials must have good mechanical properties and be non-toxic and biocompatible. Microbes, which can form biofilms, are constantly in contact with restorations. In this study, we investigate how well Candida albicans adheres to a polymethyl methacrylate (PMMA) resin base with gold (Au) nanoparticles. We synthesized Au nanoparticles and characterized them. The average size of Au nanoparticles embedded in PMMA was 11 nm. The color difference ΔE between PMMA and PMMA/Au composites was 2.7 and was still esthetically acceptable to patients. PMMA/Au surfaces are rougher and more hydrophilic than pure PMMA surfaces, and the isoelectric point of both types of surfaces was 4.3. Above the isoelectric point, PMMA/Au surfaces are more negatively charged than PMMA surfaces. The added Au nanoparticles decreased the tensile strength, while the hardness did not change significantly. Adhesion measurements showed that PMMA surfaces modified with Au nanoparticles reduced the extent of microbial adhesion of Candida albicans.

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GOST Copy
Marić I. et al. Antifungal Effect of Polymethyl Methacrylate Resin Base with Embedded Au Nanoparticles // Nanomaterials. 2023. Vol. 13. No. 14. p. 2128.
GOST all authors (up to 50) Copy
Marić I., Zore A., Rojko F., Škapin A., Štukelj R., Učakar A., Vidrih R., Veselinović V., Gotić M., Bohinc K. Antifungal Effect of Polymethyl Methacrylate Resin Base with Embedded Au Nanoparticles // Nanomaterials. 2023. Vol. 13. No. 14. p. 2128.
RIS |
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RIS Copy
TY - JOUR
DO - 10.3390/nano13142128
UR - https://doi.org/10.3390/nano13142128
TI - Antifungal Effect of Polymethyl Methacrylate Resin Base with Embedded Au Nanoparticles
T2 - Nanomaterials
AU - Marić, Ivan
AU - Zore, Anamarija
AU - Rojko, Franc
AU - Škapin, A.S.
AU - Štukelj, Roman
AU - Učakar, Aleksander
AU - Vidrih, Rajko
AU - Veselinović, Valentina
AU - Gotić, Marijan
AU - Bohinc, Klemen
PY - 2023
DA - 2023/07/22 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 2128
IS - 14
VL - 13
SN - 2079-4991
ER -
BibTex |
Cite this
BibTex Copy
@article{2023_Marić,
author = {Ivan Marić and Anamarija Zore and Franc Rojko and A.S. Škapin and Roman Štukelj and Aleksander Učakar and Rajko Vidrih and Valentina Veselinović and Marijan Gotić and Klemen Bohinc},
title = {Antifungal Effect of Polymethyl Methacrylate Resin Base with Embedded Au Nanoparticles},
journal = {Nanomaterials},
year = {2023},
volume = {13},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {jul},
url = {https://doi.org/10.3390/nano13142128},
number = {14},
pages = {2128},
doi = {10.3390/nano13142128}
}
MLA
Cite this
MLA Copy
Marić, Ivan, et al. “Antifungal Effect of Polymethyl Methacrylate Resin Base with Embedded Au Nanoparticles.” Nanomaterials, vol. 13, no. 14, Jul. 2023, p. 2128. https://doi.org/10.3390/nano13142128.
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