Open Access
Isoxazole/Isoxazoline Skeleton in the Structural Modification of Natural Products: A Review
Publication type: Journal Article
Publication date: 2023-02-02
PubMed ID:
37259376
Drug Discovery
Pharmaceutical Science
Molecular Medicine
Abstract
Isoxazoles and isoxazolines are five-membered heterocyclic molecules containing nitrogen and oxygen. Isoxazole and isoxazoline are the most popular heterocyclic compounds for developing novel drug candidates. Over 80 molecules with a broad range of bioactivities, including antitumor, antibacterial, anti-inflammatory, antidiabetic, cardiovascular, and other activities, were reviewed. A review of recent studies on the use of isoxazoles and isoxazolines moiety derivative activities for natural products is presented here, focusing on the parameters that affect the bioactivity of these compounds.
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55
Total citations:
55
Citations from 2025:
33
(60%)
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MLA
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GOST
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Wang X. et al. Isoxazole/Isoxazoline Skeleton in the Structural Modification of Natural Products: A Review // Pharmaceuticals. 2023. Vol. 16. No. 2. p. 228.
GOST all authors (up to 50)
Copy
Wang X., Hu Q., Tang H., Pan X. Isoxazole/Isoxazoline Skeleton in the Structural Modification of Natural Products: A Review // Pharmaceuticals. 2023. Vol. 16. No. 2. p. 228.
Cite this
RIS
Copy
TY - JOUR
DO - 10.3390/ph16020228
UR - https://doi.org/10.3390/ph16020228
TI - Isoxazole/Isoxazoline Skeleton in the Structural Modification of Natural Products: A Review
T2 - Pharmaceuticals
AU - Wang, Xiyue
AU - Hu, Qingyun
AU - Tang, Hui
AU - Pan, Xinhui
PY - 2023
DA - 2023/02/02
PB - MDPI
SP - 228
IS - 2
VL - 16
PMID - 37259376
SN - 1424-8247
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2023_Wang,
author = {Xiyue Wang and Qingyun Hu and Hui Tang and Xinhui Pan},
title = {Isoxazole/Isoxazoline Skeleton in the Structural Modification of Natural Products: A Review},
journal = {Pharmaceuticals},
year = {2023},
volume = {16},
publisher = {MDPI},
month = {feb},
url = {https://doi.org/10.3390/ph16020228},
number = {2},
pages = {228},
doi = {10.3390/ph16020228}
}
Cite this
MLA
Copy
Wang, Xiyue, et al. “Isoxazole/Isoxazoline Skeleton in the Structural Modification of Natural Products: A Review.” Pharmaceuticals, vol. 16, no. 2, Feb. 2023, p. 228. https://doi.org/10.3390/ph16020228.
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