Polymeric Nanocarriers of Drug Delivery Systems in Cancer Therapy
Conventional chemotherapy is the most common therapeutic method for treating cancer by the application of small toxic molecules thatinteract with DNA and causecell death. Unfortunately, these chemotherapeutic agents are non-selective and can damage both cancer and healthy tissues, producing diverse side effects, andthey can have a short circulation half-life and limited targeting. Many synthetic polymers have found application as nanocarriers of intelligent drug delivery systems (DDSs). Their unique physicochemical properties allow them to carry drugs with high efficiency, specificallytarget cancer tissue and control drug release. In recent years, considerable efforts have been made to design smart nanoplatforms, including amphiphilic block copolymers, polymer-drug conjugates and in particular pH- and redox-stimuli-responsive nanoparticles (NPs). This review is focused on a new generation of polymer-based DDSs with specific chemical functionalities that improve their hydrophilicity, drug loading and cellular interactions.Recentlydesigned multifunctional DDSs used in cancer therapy are highlighted in this review.
Top-30
Journals
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Pharmaceutics
13 publications, 5.56%
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Journal of Drug Delivery Science and Technology
13 publications, 5.56%
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Polymers
8 publications, 3.42%
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Materials
6 publications, 2.56%
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International Journal of Biological Macromolecules
5 publications, 2.14%
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International Journal of Nanomedicine
5 publications, 2.14%
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Molecules
4 publications, 1.71%
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International Journal of Pharmaceutics
4 publications, 1.71%
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ACS Applied Bio Materials
4 publications, 1.71%
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Heliyon
4 publications, 1.71%
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Journal of Nanobiotechnology
3 publications, 1.28%
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Cancers
3 publications, 1.28%
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Nanomaterials
3 publications, 1.28%
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International Journal of Polymeric Materials and Polymeric Biomaterials
3 publications, 1.28%
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ACS applied materials & interfaces
2 publications, 0.85%
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Frontiers in Pharmacology
2 publications, 0.85%
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Pharmaceuticals
2 publications, 0.85%
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Frontiers in Chemistry
2 publications, 0.85%
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3 Biotech
2 publications, 0.85%
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Polymer Bulletin
2 publications, 0.85%
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Langmuir
2 publications, 0.85%
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Coordination Chemistry Reviews
2 publications, 0.85%
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OpenNano
2 publications, 0.85%
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Biomedicine and Pharmacotherapy
2 publications, 0.85%
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Colloids and Surfaces A: Physicochemical and Engineering Aspects
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Cancer Nanotechnology
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European Polymer Journal
2 publications, 0.85%
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Journal of Materials Chemistry B
2 publications, 0.85%
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Nanoscale Advances
2 publications, 0.85%
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Publishers
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Elsevier
76 publications, 32.48%
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MDPI
48 publications, 20.51%
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Springer Nature
26 publications, 11.11%
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Taylor & Francis
22 publications, 9.4%
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American Chemical Society (ACS)
15 publications, 6.41%
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Wiley
13 publications, 5.56%
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Royal Society of Chemistry (RSC)
6 publications, 2.56%
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Frontiers Media S.A.
5 publications, 2.14%
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Bentham Science Publishers Ltd.
4 publications, 1.71%
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Pleiades Publishing
2 publications, 0.85%
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AIP Publishing
2 publications, 0.85%
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American Scientific Publishers
1 publication, 0.43%
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Korean Society of Industrial Engineering Chemistry
1 publication, 0.43%
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Hindawi Limited
1 publication, 0.43%
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IGI Global
1 publication, 0.43%
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Begell House
1 publication, 0.43%
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Annual Reviews
1 publication, 0.43%
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Institutul de Chimie Macromoleculara Petru Poni
1 publication, 0.43%
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OOO Zhurnal "Mendeleevskie Soobshcheniya"
1 publication, 0.43%
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SAGE
1 publication, 0.43%
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Turkish Chemical Society
1 publication, 0.43%
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Apex Publishing
1 publication, 0.43%
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- We do not take into account publications without a DOI.
- Statistics recalculated weekly.