Open Access
Pharmaceutics, volume 13, issue 6, pages 920
Lipophilic Polyamines as Promising Components of Liposomal Gene Delivery Systems
Publication type: Journal Article
Publication date: 2021-06-21
PubMed ID:
34205825
Pharmaceutical Science
Abstract
Gene therapy requires an effective and safe delivery vehicle for nucleic acids. In the case of non-viral vehicles, including cationic liposomes, the structure of compounds composing them determines the efficiency a lot. Currently, cationic amphiphiles are the most frequently used compounds in liposomal formulations. In their structure, which is a combination of hydrophobic and cationic domains and includes spacer groups, each component contributes to the resulting delivery efficiency. This review focuses on polycationic and disulfide amphiphiles as prospective cationic amphiphiles for gene therapy and includes a discussion of the mutual influence of structural components.
Citations by journals
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2
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Molecules
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2 publications, 22.22%
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Chemical and Pharmaceutical Bulletin
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1 publication, 11.11%
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1 publication, 11.11%
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RSC Advances
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1 publication, 11.11%
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1 publication, 11.11%
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Biomaterials Research
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1 publication, 11.11%
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Citations by publishers
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Multidisciplinary Digital Publishing Institute (MDPI)
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Multidisciplinary Digital Publishing Institute (MDPI)
4 publications, 44.44%
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Royal Society of Chemistry (RSC)
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2 publications, 22.22%
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Pharmaceutical Society of Japan
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1 publication, 11.11%
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Springer Nature
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Springer Nature
1 publication, 11.11%
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Pleiades Publishing
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Pleiades Publishing
1 publication, 11.11%
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4
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- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Puchkov P. A., Maslov M. Lipophilic Polyamines as Promising Components of Liposomal Gene Delivery Systems // Pharmaceutics. 2021. Vol. 13. No. 6. p. 920.
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Puchkov P. A., Maslov M. Lipophilic Polyamines as Promising Components of Liposomal Gene Delivery Systems // Pharmaceutics. 2021. Vol. 13. No. 6. p. 920.
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TY - JOUR
DO - 10.3390/pharmaceutics13060920
UR - https://doi.org/10.3390%2Fpharmaceutics13060920
TI - Lipophilic Polyamines as Promising Components of Liposomal Gene Delivery Systems
T2 - Pharmaceutics
AU - Puchkov, Pavel A
AU - Maslov, Michael
PY - 2021
DA - 2021/06/21 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 920
IS - 6
VL - 13
PMID - 34205825
SN - 1999-4923
ER -
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@article{2021_Puchkov,
author = {Pavel A Puchkov and Michael Maslov},
title = {Lipophilic Polyamines as Promising Components of Liposomal Gene Delivery Systems},
journal = {Pharmaceutics},
year = {2021},
volume = {13},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {jun},
url = {https://doi.org/10.3390%2Fpharmaceutics13060920},
number = {6},
pages = {920},
doi = {10.3390/pharmaceutics13060920}
}
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Puchkov, Pavel A., and Michael Maslov. “Lipophilic Polyamines as Promising Components of Liposomal Gene Delivery Systems.” Pharmaceutics, vol. 13, no. 6, Jun. 2021, p. 920. https://doi.org/10.3390%2Fpharmaceutics13060920.
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