Open Access
Polymers, volume 15, issue 3, pages 651
Poly(lactic acid) and Nanocrystalline Cellulose Methacrylated Particles for Preparation of Cryogelated and 3D-Printed Scaffolds for Tissue Engineering
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Institute of Technical Chemistry, Gottfried-Wilhelm-Leibniz University of Hannover, 30167 Hannover, Germany
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Publication type: Journal Article
Publication date: 2023-01-27
General Chemistry
Polymers and Plastics
Abstract
Different parts of bones possess different properties, such as the capacity for remodeling cell content, porosity, and protein composition. For various traumatic or surgical tissue defects, the application of tissue-engineered constructs seems to be a promising strategy. Despite significant research efforts, such constructs are still rarely available in the clinic. One of the reasons is the lack of resorbable materials, whose properties can be adjusted according to the intended tissue or tissue contacts. Here, we present our first results on the development of a toolbox, by which the scaffolds with easily tunable mechanical and biological properties could be prepared. Biodegradable poly(lactic acid) and nanocrystalline cellulose methacrylated particles were obtained, characterized, and used for preparation of three-dimensional scaffolds via cryogelation and 3D printing approaches. The composition of particles-based ink for 3D printing was optimized in order to allow formation of stable materials. Both the modified-particle cytotoxicity and the matrix-supported cell adhesion were evaluated and visualized in order to confirm the perspectives of materials application.
Citations by journals
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1
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Polymers
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Polymers
1 publication, 50%
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Journal of Applied Polymer Science
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Journal of Applied Polymer Science
1 publication, 50%
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1
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Citations by publishers
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1
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Multidisciplinary Digital Publishing Institute (MDPI)
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Multidisciplinary Digital Publishing Institute (MDPI)
1 publication, 50%
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Wiley
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Wiley
1 publication, 50%
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1
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Leonovich M. et al. Poly(lactic acid) and Nanocrystalline Cellulose Methacrylated Particles for Preparation of Cryogelated and 3D-Printed Scaffolds for Tissue Engineering // Polymers. 2023. Vol. 15. No. 3. p. 651.
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Leonovich M., Korzhikov-Vlakh V., Lavrentieva A., Pepelanova I., Korzhikova-Vlakh E., Tennikova T. B. Poly(lactic acid) and Nanocrystalline Cellulose Methacrylated Particles for Preparation of Cryogelated and 3D-Printed Scaffolds for Tissue Engineering // Polymers. 2023. Vol. 15. No. 3. p. 651.
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TY - JOUR
DO - 10.3390/polym15030651
UR - https://doi.org/10.3390%2Fpolym15030651
TI - Poly(lactic acid) and Nanocrystalline Cellulose Methacrylated Particles for Preparation of Cryogelated and 3D-Printed Scaffolds for Tissue Engineering
T2 - Polymers
AU - Leonovich, Mariia
AU - Korzhikov-Vlakh, Viktor
AU - Lavrentieva, Antonina
AU - Pepelanova, Iliyana
AU - Korzhikova-Vlakh, Evgenia
AU - Tennikova, T. B.
PY - 2023
DA - 2023/01/27 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 651
IS - 3
VL - 15
SN - 2073-4360
ER -
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@article{2023_Leonovich,
author = {Mariia Leonovich and Viktor Korzhikov-Vlakh and Antonina Lavrentieva and Iliyana Pepelanova and Evgenia Korzhikova-Vlakh and T. B. Tennikova},
title = {Poly(lactic acid) and Nanocrystalline Cellulose Methacrylated Particles for Preparation of Cryogelated and 3D-Printed Scaffolds for Tissue Engineering},
journal = {Polymers},
year = {2023},
volume = {15},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {jan},
url = {https://doi.org/10.3390%2Fpolym15030651},
number = {3},
pages = {651},
doi = {10.3390/polym15030651}
}
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Leonovich, Mariia, et al. “Poly(lactic acid) and Nanocrystalline Cellulose Methacrylated Particles for Preparation of Cryogelated and 3D-Printed Scaffolds for Tissue Engineering.” Polymers, vol. 15, no. 3, Jan. 2023, p. 651. https://doi.org/10.3390%2Fpolym15030651.