Open Access
Sensors, volume 22, issue 8, pages 2893
A Three-Reagent “Green” Paper-Based Analytical Device for Solid-Phase Spectrometric and Colorimetric Determination of Dihydroquercetin
Publication type: Journal Article
Publication date: 2022-04-09
PubMed ID:
35458878
Biochemistry
Analytical Chemistry
Atomic and Molecular Physics, and Optics
Electrical and Electronic Engineering
Instrumentation
Abstract
Microfluidic paper-based analytical devices (µPADs) represent one of the promising green analytical strategies for low-cost and simple determination of various analytes. The actual task is the development of such devices for quantitation of antioxidants, e.g., flavonoids. In this paper, possibilities of a novel three-reagent µPAD including silver nitrate, 4-nitrophenyldiazonium tetrafluoroborate, and iron(III) chloride as reagents are assessed with respect to the determination of dihydroquercetin. It is shown that all the three reagents produce different colorimetric responses that can be detected by a mini-spectrophotometer–monitor calibrator or by a smartphone. The method is applicable to direct measuring high contents of dihydroquercetin (the linearity range is 0.026–1 mg mL−1, and the limit of detection is 7.7 µg mL−1), which is favorable for many dietary supplements. The analysis of a food supplement was possible with the relative standard deviations of 9–26%, which is satisfactory for quantitative and semiquantitative determinations. It was found that plotting a calibration graph in 3D space of the three reagents’ responses allows us to distinguish dihydroquercetin from its close structural analogue, quercetin.
Citations by journals
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Analytical Sciences
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Analytical Sciences
2 publications, 50%
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Journal of Analytical Chemistry
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Journal of Analytical Chemistry
1 publication, 25%
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International Journal of Molecular Sciences
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International Journal of Molecular Sciences
1 publication, 25%
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Citations by publishers
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Japan Society for Analytical Chemistry
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Japan Society for Analytical Chemistry
2 publications, 50%
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Pleiades Publishing
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Pleiades Publishing
1 publication, 25%
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Multidisciplinary Digital Publishing Institute (MDPI)
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Multidisciplinary Digital Publishing Institute (MDPI)
1 publication, 25%
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Apyari V. et al. A Three-Reagent “Green” Paper-Based Analytical Device for Solid-Phase Spectrometric and Colorimetric Determination of Dihydroquercetin // Sensors. 2022. Vol. 22. No. 8. p. 2893.
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Apyari V., Furletov A. A., Kalinin V. I., Dmitrienko S. G., Zolotov D. A. A Three-Reagent “Green” Paper-Based Analytical Device for Solid-Phase Spectrometric and Colorimetric Determination of Dihydroquercetin // Sensors. 2022. Vol. 22. No. 8. p. 2893.
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TY - JOUR
DO - 10.3390/s22082893
UR - https://doi.org/10.3390%2Fs22082893
TI - A Three-Reagent “Green” Paper-Based Analytical Device for Solid-Phase Spectrometric and Colorimetric Determination of Dihydroquercetin
T2 - Sensors
AU - Kalinin, Vyacheslav I
AU - Dmitrienko, Stanislava G
AU - Apyari, Vladimir
AU - Furletov, Aleksei A
AU - Zolotov, Denis A
PY - 2022
DA - 2022/04/09 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 2893
IS - 8
VL - 22
PMID - 35458878
SN - 1424-3210
SN - 1424-8220
ER -
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@article{2022_Apyari,
author = {Vyacheslav I Kalinin and Stanislava G Dmitrienko and Vladimir Apyari and Aleksei A Furletov and Denis A Zolotov},
title = {A Three-Reagent “Green” Paper-Based Analytical Device for Solid-Phase Spectrometric and Colorimetric Determination of Dihydroquercetin},
journal = {Sensors},
year = {2022},
volume = {22},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {apr},
url = {https://doi.org/10.3390%2Fs22082893},
number = {8},
pages = {2893},
doi = {10.3390/s22082893}
}
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MLA
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Apyari, Vladimir, et al. “A Three-Reagent “Green” Paper-Based Analytical Device for Solid-Phase Spectrometric and Colorimetric Determination of Dihydroquercetin.” Sensors, vol. 22, no. 8, Apr. 2022, p. 2893. https://doi.org/10.3390%2Fs22082893.