Aptamer-Based Technologies for Parasite Detection
Centuries of scientific breakthroughs have brought us closer to understanding and managing the spread of parasitic diseases. Despite ongoing technological advancements in the detection, treatment, and control of parasitic illnesses, their effects on animal and human health remain a major concern worldwide. Aptamers are single-stranded oligonucleotides whose unique three-dimensional structures enable them to interact with high specificity and affinity to a wide range of targets. In recent decades, aptamers have emerged as attractive alternatives to antibodies as therapeutic and diagnostic agents. Due to their superior stability, reusability, and modifiability, aptamers have proven to be effective bioreceptors for the detection of toxins, contaminants, biomarkers, whole cells, pathogens, and others. As such, they have been integrated into a variety of electrochemical, fluorescence, and optical biosensors to effectively detect whole parasites and their proteins. This review offers a summary of the various types of parasite-specific aptamer-based biosensors, their general mechanisms and their performance.
Top-30
Citations by journals
1
2
|
|
Talanta
2 publications, 20%
|
|
ACS Sensors
1 publication, 10%
|
|
Biosensors
1 publication, 10%
|
|
ACS Measurement Science Au
1 publication, 10%
|
|
Food Research International
1 publication, 10%
|
|
International Journal of Biological Macromolecules
1 publication, 10%
|
|
Russian Chemical Reviews
1 publication, 10%
|
|
Journal of Genetic Engineering and Biotechnology
1 publication, 10%
|
|
International Journal of Molecular Sciences
1 publication, 10%
|
|
1
2
|
Citations by publishers
1
2
3
4
5
|
|
Elsevier
5 publications, 50%
|
|
American Chemical Society (ACS)
2 publications, 20%
|
|
Multidisciplinary Digital Publishing Institute (MDPI)
2 publications, 20%
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 10%
|
|
1
2
3
4
5
|
- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.