том 4 издание 9 страницы 1099-1123

pH-sensitive liposomes for drug delivery in cancer treatment

Тип публикацииJournal Article
Дата публикации2013-09-11
scimago Q2
wos Q3
БС1
SJR0.427
CiteScore4.1
Impact factor2.2
ISSN20415990, 20416008
Pharmaceutical Science
Краткое описание

In recent years, liposomes have been employed with growing success as pharmaceutical carriers for antineoplastic drugs. One specific strategy used to enhance in vivo liposome-mediated drug delivery is the improvement of intracytoplasmic delivery. In this context, pH-sensitive liposomes (pHSLip) have been designed to explore the endosomal acidification process, which may lead to a destabilization of the liposomes, followed by a release of their contents into the cell cytoplasm. This review considers the current status of pHSLip development and its applicability in cancer treatment, focusing on the mechanisms of pH sensitivity and liposomal composition of pHSLip. The final section will discuss the application of these formulations in both in vitro and in vivo studies of antitumor efficacy.

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ГОСТ |
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Ferreira D. D. S. et al. pH-sensitive liposomes for drug delivery in cancer treatment // Therapeutic Delivery. 2013. Vol. 4. No. 9. pp. 1099-1123.
ГОСТ со всеми авторами (до 50) Скопировать
Ferreira D. D. S., Lopes S. C. D. A., Franco M. S., Oliveira M. C. pH-sensitive liposomes for drug delivery in cancer treatment // Therapeutic Delivery. 2013. Vol. 4. No. 9. pp. 1099-1123.
RIS |
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TY - JOUR
DO - 10.4155/tde.13.80
UR - https://doi.org/10.4155/tde.13.80
TI - pH-sensitive liposomes for drug delivery in cancer treatment
T2 - Therapeutic Delivery
AU - Ferreira, Diego dos Santos
AU - Lopes, Sávia Caldeira de Araújo
AU - Franco, Marina Santiago
AU - Oliveira, Mônica Cristina
PY - 2013
DA - 2013/09/11
PB - Taylor & Francis
SP - 1099-1123
IS - 9
VL - 4
PMID - 24024511
SN - 2041-5990
SN - 2041-6008
ER -
BibTex |
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BibTex (до 50 авторов) Скопировать
@article{2013_Ferreira,
author = {Diego dos Santos Ferreira and Sávia Caldeira de Araújo Lopes and Marina Santiago Franco and Mônica Cristina Oliveira},
title = {pH-sensitive liposomes for drug delivery in cancer treatment},
journal = {Therapeutic Delivery},
year = {2013},
volume = {4},
publisher = {Taylor & Francis},
month = {sep},
url = {https://doi.org/10.4155/tde.13.80},
number = {9},
pages = {1099--1123},
doi = {10.4155/tde.13.80}
}
MLA
Цитировать
Ferreira, Diego dos Santos, et al. “pH-sensitive liposomes for drug delivery in cancer treatment.” Therapeutic Delivery, vol. 4, no. 9, Sep. 2013, pp. 1099-1123. https://doi.org/10.4155/tde.13.80.