Open Access
Open access
International Journal of Tuberculosis and Lung Disease, volume 26, issue 11, pages 1023-1032

Improving access to affordable quality-assured inhaled medicines in low- and middle-income countries

M. Stolbrink 1
M. J. Chinouya 2
S Jayasooriya 3
R. Nightingale 4
L. Evans-Hill 5
K. Allan 6
H ALLEN 7
J. Balen 8
T Beacon 9
K Bissell 10
J Chakaya 11
C.-Y. Chiang 12
M. Cohen 13
G. Devereux 14
A El Sony 15
D.M. G. HALPIN 16
J. R. Hurst 17
C. Kiprop 18
A. Lawson 19
C Macé 20
A. Makhanu 18
P. Makokha 18
R Masekela 21
H Meme 22
E M Khoo 23
R Nantanda 24
S Pasternak 25
C. Perrin 20
H Reddel 26
S Rylance 27
P. Schweikert 19
C. Were 25
S Williams 28
T Winders 29
A. Yorgancioglu 30
G B Marks 31
K. Mortimer 32
Show full list: 37 authors
4
 
Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK, IcFEM Dreamland Mission Hospital, Kimilili, Kenya
5
 
Nifty Fox Creative, Sheffield, UK
6
 
Healthcare Consultant, Medical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, The Gambia
7
 
Medical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, The Gambia
9
 
Medical Aid International, Bedford, UK
13
 
Asociación Latinoamericana del Tórax, Forum of International Respiratory Societies, Guatemala
15
 
The Epidemiological Laboratory (Epi-Lab) for Public Health, Research and Development, Khartoum Sudan
18
 
IcFEM Dreamland Mission Hospital, Kimilili, Kenya
20
 
International Union against Tuberculosis and Lung Disease, Paris, France
23
 
Department of Primary Care Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia, International Primary Care Respiratory Group, Larbert, Scotland, UK
26
 
The Woolcock Institute of Medical Research, The University of Sydney, Sydney, NSW, Australia, Global Initiative for Asthma (GINA), Fontana, WI, USA
27
 
Noncommunicable Diseases Department, World Health Organization, Geneva, Switzerland
28
 
International Primary Care Respiratory Group, Larbert, Scotland, UK
29
 
Global Allergy & Airways Patient Platform, Vienna, Austria
30
 
Department of Pulmonology, Celal Bayar University Medical Faculty, Manisa, Turkey, Global Alliance Against Chronic Respiratory Diseases, Geneva, Switzerland
Publication typeJournal Article
Publication date2022-11-01
scimago Q1
SJR0.952
CiteScore4.9
Impact factor3.4
ISSN10273719, 18157920
Infectious Diseases
Pulmonary and Respiratory Medicine
Abstract

BACKGROUND: Access to affordable inhaled medicines for chronic respiratory diseases (CRDs) is severely limited in low- and middle-income countries (LMICs), causing avoidable morbidity and mortality. The International Union Against Tuberculosis and Lung Disease convened a stakeholder meeting on this topic in February 2022.METHODS: Focused group discussions were informed by literature and presentations summarising experiences of obtaining inhaled medicines in LMICs. The virtual meeting was moderated using a topic guide around barriers and solutions to improve access. The thematic framework approach was used for analysis.RESULTS: A total of 58 key stakeholders, including patients, healthcare practitioners, members of national and international organisations, industry and WHO representatives attended the meeting. There were 20 pre-meeting material submissions. The main barriers identified were 1) low awareness of CRDs; 2) limited data on CRD burden and treatments in LMICs; 3) ineffective procurement and distribution networks; and 4) poor communication of the needs of people with CRDs. Solutions discussed were 1) generation of data to inform policy and practice; 2) capacity building; 3) improved procurement mechanisms; 4) strengthened advocacy practices; and 5) a World Health Assembly Resolution.CONCLUSION: There are opportunities to achieve improved access to affordable, quality-assured inhaled medicines in LMICs through coordinated, multi-stakeholder, collaborative efforts.

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