Ceska a Slovenska Farmacie, volume 71, issue 3, pages 91-97
Metronomická terapie v léčbě nádorových onemocnění
Mazánková D., Bárková V., Mazánek P.
Publication type: Journal Article
Publication date: 2022-11-18
Journal:
Ceska a Slovenska Farmacie
scimago Q3
SJR: 0.162
CiteScore: 0.9
Impact factor: —
ISSN: 12107816, 18054439
Pharmaceutical Science
Abstract
Metronomic therapy is a therapeutic method in selected oncological diseases, using long-term administration of low doses of drugs with direct or indirect antitumor effect. In addition, to direct cytotoxic eradication of tumor cells, metronomic therapy can very strongly affect the tumor microenvironment; it also has an immunomodulatory and antiangiogenic effect. Its minimal toxic profile allows for use in patients with severe organ dysfunctions and directly impacts the quality of life and social inclusion of oncological patients.
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