Ceska a Slovenska Farmacie, volume 71, issue 3, pages 98-102

The effect of Aronia melanocarpa extract on the phospholipid composition of the rat myocardium during stress

Shvets V., Maslak H., Davydov V., Berest H., Nosulenko I.
Publication typeJournal Article
Publication date2022-11-18
scimago Q3
SJR0.162
CiteScore0.9
Impact factor
ISSN12107816, 18054439
Pharmaceutical Science
Abstract

The research was performed on 80 male rats of the Wistar line. Animals of two age groups were used: adults (10–12 months) and old (22–25 months). The obtained data show that the development of immobilization stress in adult and aged rats are accompanied by the formation of a characteristic complex of changes in the phospholipid composition of the myocardium. Intraperitoneal injection of the chokeberry extract (Aronia melanocarpa) at a dose of 0.2 g/kg 60 minutes before the immobilization has limited stress modulation of myocardial phospholipid composition in aged animals. Thus, the extract of Aronia melanocarpa increases the myocardial resistance to the injury effect of stress.

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