Protolytic and potential antithyroid properties of thioglycolurils and fused azolo-1,2,4-triazines

Ivolgina V.A., Popov L.D., Gazieva G.A., Kravchenko A.N.
Тип документаJournal Article
Дата публикации2020-11-01
Название журналаRussian Chemical Bulletin
ИздательSpringer Nature
КвартильQ3
ISSN10665285, 15739171
  • General Chemistry
Краткое описание
The protolytic properties and reactions with molecular iodine and blood serum proteins of 5,7-dimethyltetrahydro-1H-imidazo[4,5-e]-1,2,4-triazine-3,6(2H,4H)-dithione and (R)-1,3-dialkyl-4-[(2-hydroxybenzylidene)amino]-5-thioxohexahydroimidazo[4,5-d]imidazol-2(1H)-ones were studied. These compounds exhibit different chemical reactivities towards molecular iodine. The binding constants between these compounds and serum albumin attest to a considerable protein affinity of the compounds. The properties of the thiones make them promising as antithyroid agents.
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1. Ivolgina V.A. и др. Protolytic and potential antithyroid properties of thioglycolurils and fused azolo-1,2,4-triazines // Russian Chemical Bulletin. 2020. Т. 69. № 11. С. 2215–2221.
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TY - JOUR

DO - 10.1007/s11172-020-3024-z

UR - http://dx.doi.org/10.1007/s11172-020-3024-z

TI - Protolytic and potential antithyroid properties of thioglycolurils and fused azolo-1,2,4-triazines

T2 - Russian Chemical Bulletin

AU - Ivolgina, V. A.

AU - Popov, L. D.

AU - Gazieva, G. A.

AU - Kravchenko, A. N.

PY - 2020

DA - 2020/11

PB - Springer Science and Business Media LLC

SP - 2215-2221

IS - 11

VL - 69

SN - 1066-5285

SN - 1573-9171

ER -

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@article{2020,

doi = {10.1007/s11172-020-3024-z},

url = {https://doi.org/10.1007%2Fs11172-020-3024-z},

year = 2020,

month = {nov},

publisher = {Springer Science and Business Media {LLC}},

volume = {69},

number = {11},

pages = {2215--2221},

author = {V. A. Ivolgina and L. D. Popov and G. A. Gazieva and A. N. Kravchenko},

title = {Protolytic and potential antithyroid properties of thioglycolurils and fused azolo-1,2,4-triazines}

}

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Ivolgina, V. A. et al. “Protolytic and Potential Antithyroid Properties of Thioglycolurils and Fused Azolo-1,2,4-Triazines.” Russian Chemical Bulletin 69.11 (2020): 2215–2221. Crossref. Web.