Oncology

Research interests = Creation of models of tumor growth (immunodeficient Balb/c nude mice, Danio rerio embryos, cultural models) and research on these models of antitumor activity and mechanisms of action of new agents = Master's program of the Department of Biochemistry of the RUDN "Creation and development of drugs" In a broad sense, the scientific interests of the laboratory are at the junction of experimental oncology, biochemistry and pharmacology. We help researchers in the field of medical chemistry, biotechnology and fundamental oncology to evaluate the effect of new agents on tumor growth (cytotoxic, antitumor effect) and to study certain aspects of the mechanisms of action of potential drugs

Development of nanoscale targeted drug delivery systems, production of recombinant proteins and peptides, conducting preclinical tests (in vitro and in vivo)

Regenerative medicine for cancer patients.

Investigation of the mechanisms of chemical carcinogenesis, investigation of the epigenetic activity of xenobiotics, conducting preclinical tests, secondary carcinogenesis, etc.

The main activities of the laboratory are: molecular design of kinase inhibitors; molecular design of autophagy inhibitors; chimeric molecules oriented to proteolysis (PROTAC); high-performance phenotypic screening.

A project to study the interactions of tumor cells and the microenvironment in response to immunotherapy using 3D cellular models of human breast and brain tumors.