LMC Bio

The project is aimed at developing new chemical approaches to the synthesis of biocompatible phosphorescent phosphors based on square-square tweezer and orthometallic complexes Pt(II) and Au(III), in which the phenomenon of Aggregation Inducedemission (AIE) is realized, allowing targeted modification of the photophysical characteristics of the initial chromophores.

The project is aimed at a systematic study of the effect of phosphorescence flaring (or amplification) caused by aggregation (the "aggregation-induced phosphorescence emission/enhancement" effect, AIPE) using the example of three series of phosphorescent organometallic complexes based on platinum(II), gold(III) and iridium(III) embedded in block copolymer micelles a core-shell structural type based on amphiphilic diblock copolymers with a variable hydrophobic block and a hydrophilic block based on polyethylene glycol. The main distinguishing feature of the project is the implementation of the idea of spatial localization of the AIPE process in a strictly limited volume of polymer nanoparticles, which are diblock copolymer micelles of the "core-shell" structural type.

Transition metal complexes have a huge potential for use as luminescent materials in modern technologies, in particular in OLED technologies and functional biomaging, and the development of methods for the directed synthesis of new photoactive materials with controlled properties is currently one of the most promising areas of chemical science. It should be noted that phosphorescent organometallic emitters have a number of advantages in comparison with traditionally used organic fluorophores, which is due to the triplet nature of emission transitions of this class of compounds, characterized, in particular, by large values of Stokes emission shifts and micro- and millisecond intervals of excited state lifetimes. These differences open up new opportunities for the practical application of this class of compounds in technologies using the energy of light radiation, and the search for new triplet emitters with adjustable emission parameters is undoubtedly an urgent task that fully corresponds to the world level of research.