Rajasthan Technical University

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Short name
RTU
Country, city
India, Kota
Publications
915
Citations
7 551
h-index
38
Top-3 organizations
Top-3 foreign organizations

Most cited in 5 years

Yadav M., Perumal M., Srinivas M.
Chaos, Solitons and Fractals scimago Q1 wos Q1
2020-10-01 citations by CoLab: 124 Abstract  
In this paper, we are working on a pandemic of novel coronavirus (COVID-19). COVID-19 is an infectious disease, it creates severe damage in the lungs. COVID-19 causes illness in humans and has killed many people in the entire world. However, this virus is reported as a pandemic by the World Health Organization (WHO) and all countries are trying to control and lockdown all places. The main objective of this work is to solve the five different tasks such as I) Predicting the spread of coronavirus across regions. II) Analyzing the growth rates and the types of mitigation across countries. III) Predicting how the epidemic will end. IV) Analyzing the transmission rate of the virus. V) Correlating the coronavirus and weather conditions. The advantage of doing these tasks to minimize the virus spread by various mitigation, how well the mitigations are working, how many cases have been prevented by this mitigations, an idea about the number of patients that will recover from the infection with old medication, understand how much time will it take to for this pandemic to end, we will be able to understand and analyze how fast or slow the virus is spreading among regions and the infected patient to reduce the spread based clear understanding of the correlation between the spread and weather conditions. In this paper, we propose a novel Support Vector Regression method to analysis five different tasks related to novel coronavirus. In this work, instead of simple regression line we use the supported vectors also to get better classification accuracy. Our approach is evaluated and compared with other well-known regression models on standard available datasets. The promising results demonstrate its superiority in both efficiency and accuracy.
Kumar S., Sharma B., Sharma V.K., Sharma H., Bansal J.C.
2020-12-01 citations by CoLab: 90 Abstract  
Agriculture is one of the prime sources of economy and a large community is involved in cropping various plants based on the environmental conditions. However, a number of challenges are faced by the farmers including different diseases of plants. The detection and prevention of plant diseases are the serious concern and should be treated well on time for increasing the productivity. Therefore, an automated plant disease detection system can be more beneficial for monitoring the plants. Generally, the most diseases may be detected and classified from the symptoms appeared on the leaves. For the same, extraction of relevant features plays an important role. A number of methods exists to generate high dimensional features to be used in plant disease classification problem such as SPAM, CHEN, LIU, and many more. However, generated features also include unrelated and inessential features that lead to degradation in performance and computational efficiency of a classification problem. Therefore, the choice of notable features from the high dimensional feature set is required to increase the computational efficiency and accuracy of a classifier. This paper introduces a novel exponential spider monkey optimization which is employed to fix the significant features from high dimensional set of features generated by SPAM. Furthermore, the selected features are fed to support vector machine for classification of plants into diseased plants and healthy plants using some important characteristics of the leaves. The experimental outcomes illustrate that the selected features by Exponential SMO effectively increase the classification reliability of the classifier in comparison to the considered feature selection approaches.
Mishra A.M., Purohit S.D., Owolabi K.M., Sharma Y.D.
Chaos, Solitons and Fractals scimago Q1 wos Q1
2020-09-01 citations by CoLab: 76 Abstract  
In this article, we develop a mathematical model considering susceptible, exposed, infected, asymptotic, quarantine/isolation and recovered classes as in case of COVID-19 disease. The facility of quarantine/isolation have been provided to both exposed and infected classes. Asymptotic individuals either recovered without undergo treatment or moved to infected class after some duration. We have formulated the reproduction number for the proposed model. Elasticity and sensitivity analysis indicates that model is more sensitive towards the transmission rate from exposed to infected classes rather than transmission rate from susceptible to exposed class. Analysis of global stability for the proposed model is studied through Lyapunov's function.
Shekhawat S.S., Sharma H., Kumar S., Nayyar A., Qureshi B.
IEEE Access scimago Q1 wos Q2 Open Access
2021-01-07 citations by CoLab: 68 Abstract  
Feature selection is a technique commonly used in Data Mining and Machine Learning. Traditional feature selection methods, when applied to large datasets, generate a large number of feature subsets. Selecting optimal features within this high dimensional data space is time-consuming and negatively affects the system's performance. This paper proposes a new binary Salp Swarm Algorithm (bSSA) for selecting the best feature set from transformed datasets. The proposed feature selection method first transforms the original data-set using Principal Component Analysis (PCA) and fast Independent Component Analysis (fastICA) based hybrid data transformation methods; next, a binary Salp Swarm optimizer is used for finding the best features. The proposed feature selection approach improves accuracy and eliminates the selection of irrelevant features. We validate our technique on fifteen different benchmark data sets. We conduct an extensive study to measure the performance and feature selection accuracy of the proposed technique. The proposed bSSA is compared to Binary Genetic Algorithm (bGA), Binary Binomial Cuckoo Search (bBCS), Binary Grey Wolf Optimizer (bGWO), Binary Competitive Swarm Optimizer (bCSO), and Binary Crow Search Algorithm (bCSA). The proposed method attains a mean accuracy of 95.26% with 7.78% features on PCA-fastICA transformed datasets. The results show that bSSA outperforms the existing methods for the majority of the performance measures.
Singh P., Meena N.K., Yang J., Vega-Fuentes E., Bishnoi S.K.
Applied Energy scimago Q1 wos Q1
2020-11-01 citations by CoLab: 64 Abstract  
The optimal integration of distributed energy resources (DERs) is a multiobjective and complex combinatorial optimization problem that conventional optimization methods cannot solve efficiently. This paper reviews the existing DER integration models, optimization and multi-criteria decision-making approaches. Further to that, a recently developed monarch butterfly optimization method is introduced to solve the problem of DER mix in distribution systems. A new multiobjective DER integration problem is formulated to find the optimal sites, sizes and mix (dispatchable and non-dispatchable) for DERs considering multiple key performance objectives. Besides, a hybrid method that combines the monarch butterfly optimization and the technique for order of preference by similarity to ideal solution (TOPSIS) is proposed to solve the formulated large-scale multi-criteria decision-making problem. Whilst the meta-heuristic optimization method generates non-dominated solutions (creating Pareto-front), the TOPSIS approach selects that with the most promising outcome from a large number of alternatives. The effectiveness of this approach is verified by solving single and multiobjective dispatchable DER integration problems over the benchmark 33-bus distribution system and the performance is compared with the existing optimization methods. The proposed model of DER mix and the optimization technique significantly improve the system performance in terms of average annual energy loss reduction by 78.36%, mean node voltage deviation improvement by 9.59% and average branches loadability limits enhancement by 50%, and minimized the power fluctuation induced by 48.39% renewable penetration. The proposed optimization techniques outperform the existing methods with promising exploration and exploitation abilities to solve engineering optimization problems. • Introduces Monarch butterfly optimization for solving DER integration problems. • A novel mix with technique for order of preference by similarity to ideal solution. • A new multi-criteria decision-making problem for DER mix in distribution networks. • Comparison of proposed and existing methods on standard 33-bus distribution system. • Notable annual energy loss reduction (78.36%) with improved stability and voltages.
Khatti J., Grover K.S.
2023-11-01 citations by CoLab: 63 Abstract  
A comparison between deep learning and standalone models in predicting the compaction parameters of soil is presented in this research. One hundred and ninety and fifty-three soil samples were randomly picked up from two hundred and forty-three soil samples to create training and validation datasets, respectively. The performance and accuracy of the models were measured by root mean square error (RMSE), coefficient of determination (R2), Pearson product-moment correlation coefficient (r), mean absolute error (MAE), variance accounted for (VAF), mean absolute percentage error (MAPE), weighted mean absolute percentage error (WMAPE), a20-index, index of scatter (IOS), and index of agreement (IOA). Comparisons between standalone models demonstrate that the model MD 29 in Gaussian process regression (GPR) and model MD 101 in support vector machine (SVM) can achieve over 96% of accuracy in predicting the optimum moisture content (OMC) and maximum dry density (MDD) of soil, and outperformed other standalone models. The comparison between deep learning models shows that the models MD 46 and MD 146 in long short-term memory (LSTM) predict OMC and MDD with higher accuracy than ANN models. However, the LSTM models outperformed the GPR models in predicting the compaction parameters. The sensitivity analysis illustrates that fine content (FC), specific gravity (SG), and liquid limit (LL) highly influence the prediction of compaction parameters.
Saini P., Gidwani L.
Journal of Energy Storage scimago Q1 wos Q1
2022-01-01 citations by CoLab: 58 Abstract  
Battery energy storage system technique work as alternative load during low demand situation by storing the excess generation and work as alternative power generation source by discharging the stored generation during peak demand. In this work, a comprehensive assessment is performed for battery energy storage system installation and their capacities selection by utilizing the Photovoltaics (PV) output in radial distribution network by considering commercial, residential and industrial time varying load models. The objective of proposed the work is to reduce annual energy losses, mitigate reverse power flow and overvoltage problem and provide peak power dispatch during peak demand in distribution network. A comparative investigation is performed by considering PV and PV-BESS case for each type of load model. Furthermore, the battery energy storage system (BESS) function developed that decide the time and capacity of charging and discharging in order to manage PV penetration and improve the voltage profile, minimize the daily energy losses and control the reverse power flow in the distribution system without deviating the operational limits. A voltage based sensitivity method is developed at initial step to find out the most prominent node in distribution network for BESS installation. The objective of the problem is resolved by genetic algorithm to find out the optimal solution and to assess the comparison of technical parameters between considered cases. The simulation results on IEEE 69 bus test system show that the proposed methodology for BESS placement decreases the annual energy losses, enhances the PV penetration and reduces the overvoltage and mitigate the reverse power flow. Results of this paper also shows that it is possible to dispatch peak power during the peak load hours for each type of load model. • A technical assessment is performed for optimal allocation of BESS in distribution network. • Time varying load models are considered for BESS allocation in distribution network. • A sensitivity-based method is used to identify the prominent location for BESS allocation. • BESS charging and discharging function is formulated for optimal daily scheduling of BESS units.
Shyamsunder, Bhatter S., Jangid K., Abidemi A., Owolabi K.M., Purohit S.D.
2023-03-01 citations by CoLab: 51 Abstract  
This study proposes a new fractional mathematical model to study the impact of vaccination on COVID-19 outbreaks by categorizing infected people into non-vaccinated, first dose-vaccinated, and second dose-vaccinated groups and exploring the transmission dynamics of the disease outbreaks. We present a non-linear integer order mathematical model of COVID-19 dynamics and modify it by introducing Caputo fractional derivative operator. We start by proving the good state of the model and then calculating its reproduction number. The Caputo fractional-order model is discretized by applying a reliable numerical technique. The model is proven to be stable. The classical model is fitted to the corresponding cumulative number of daily reported cases during the vaccination regime in India between 01 August 2021 and 21 July 2022. We explore the sensitivities of the reproduction number with respect to the model parameters. It is shown that the effective transmission rate and the recovery rate of unvaccinated infected individuals are the most sensitive parameters that drive the transmission dynamics of the pandemic in the population. Numerical simulations are used to demonstrate the applicability of the proposed fractional mathematical model via the memory index at different values of 0.7,0.8,0.9 and 1. We discuss the epidemiological significance of the findings and provide perspectives on future health policy tendencies. For instance, efforts targeting a decrease in the transmission rate and an increase in the recovery rate of non-vaccinated infected individuals are required to ensure virus-free population. This can be achieved if the population strictly adhere to precautionary measures, and prompt and adequate treatment is provided for non-vaccinated infectious individuals. Also, given the ongoing community spread of COVID-19 in India and almost the pandemic-affected countries worldwide, the need to scale up the effort of mass vaccination policy cannot be overemphasized in order to reduce the number of unvaccinated infections with a view to halting the transmission dynamics of the disease in the population.
Agrawal P., Dadheech P.K., Jat R.N., Nisar K.S., Bohra M., Purohit S.D.
2021-02-01 citations by CoLab: 43 Abstract  
In the current framework, a computational simulation for 2-D γ − A L 2 O 3 nanofluid flow over a stretching surface with Marangoni convection embedded in porous medium is presented. Here the magnetic field and nonlinear thermal radiation is also applied with heat source/sink. A comparative analysis is presented for water and ethylene glycol based γ − A L 2 O 3 nanofluids. A mathematical model of the present problem with appropriate boundary conditions is given in terms of partial differential equations. Numerical calculation of this model is computed by the Runge-Kutta method of order four with shooting technique by utilizing the suitable similarity transformations. Temperature and velocity fields are studied analytically and illustrated by the graphs for various flow control parameters. Results shows that the temperature profile of the γ − A l 2 O 3 − H 2 O nanofluid is always higher than the γ − A l 2 O 3 − C 2 H 6 O 2 nanofluid hence γ − A l 2 O 3 − C 2 H 6 O 2 nanofluid becomes more significant in cooling process then γ − A l 2 O 3 − H 2 O nanofluid.
Singh J., Kumar D., Purohit S.D., Mishra A.M., Bohra M.
2020-11-20 citations by CoLab: 42
Hussain A., Hussain A.
Current Drug Therapy scimago Q3 wos Q4
2025-02-14 citations by CoLab: 0 Abstract  
Mpox is an emerging zoonotic viral infection caused by the Monkeypox virus that has become a global health threat. Though vaccines for smallpox are available and used, therapeutics are scarce for Mpox, and increasing drug-resistant strains are found. Among recent advances in antiviral therapy, amphiphilic small molecules have been found, which could potentially serve as inhibitors of viral replication. This editorial describes the challenges presented by the Mpox virus as it evolves over time and delves deeper into more recent studies based on computational drug design and nano-assembly. In this regard, small amphiphilic molecules have established their potential to inhibit viral entry and replication through interaction with viral envelope proteins. This editorial also describes the current state of research into such small molecules. It underlines their promise in the potential struggle against Mpox and explores their mechanisms of action, therapeutic efficacy, and prospects for clinical application.
Zafar R., Kanungo V., Pandey R., Metya S.K., Tharani L., Singh G.
Journal of Optics (India) scimago Q3 wos Q3
2025-02-11 citations by CoLab: 0 Abstract  
In this article, a novel asymmetrical split ring resonators-based Metal-Insulator-Metal (MIM) plasmonic refractive index sensor is numerically investigated. The MIM waveguide is coupled to split ring resonators on both sides. The presence of a split in the ring resonator generates a strong localized field in the vicinity of resonance condition and supports a distinctive resonance profile known as Fano resonance. The novelty lies in terms of induced asymmetricity due to the changes in the position of a split in the second resonator with respect to a split in the first ring resonator. This specific arrangement helps to tune the Fano resonance through a single parameter i.e. position of split in 2nd resonator. The performance of the sensor is measured through sensitivity and Figure of merit (FOM). A large value of Sensitivity S = 1630 nm/RIU and FOM = 180 is obtained with the proposed sensor. The enhanced sensitivity and FOM demonstrate the sensors’ ability for detecting low concentration of analytes.
Bhardwaj A., Dhull S., Kumawat S., Joshi G.P., Gupta D., Yadav D.
Green Materials scimago Q3 wos Q3
2025-02-11 citations by CoLab: 0 Abstract  
Fibre composites are emerging as a prominent player in curbing materials need along with the solving environmental degradation by using waste material as the as the substrate in composite. Because of their potential to improve material qualities, aluminium-based composites that include natural fibres and reinforcing agents have attracted a lot of attention. The goal of this research is to create a new aluminium composite by combining silicon carbide (SiC) particles with banana stem fibres. Examining how these additions affect the final composite's mechanical, thermal, and structural characteristics is the main goal. Banana stem fibres and SiC particles were first prepared as part of the fabrication process, and then they were cast into an aluminium matrix. When compared to traditional aluminium, the composite's strength and stiffness were significantly improved by subsequent characterisation using mechanical testing and microscopy techniques. The noted alterations in the material's microstructure and characteristics offer important new information on the possible uses of these composite in various industrial applications. This study opens the door for environmentally friendly and high-performing materials by highlighting the potential of using SiC particles and banana stem fibres as reinforcing agents in aluminium-based composites.
Hussain A., Hussain A.
2025-02-06 citations by CoLab: 0 Abstract  
Probiotics have appeared as effective immunotherapeutic adjuvants that influence host immune responses to viral infections. The latest study has shown that probiotics can improve innate and adaptive immunity by activating dendritic cells, producing interferons, and modulating proinflammatory cytokines. Probiotics can be used as adjuvants in viral immunotherapy to enhance mucosal immunity, which is critical for battling emerging infectious illnesses such as monkeypox. The antiviral potency of probiotics, specifically with standard therapies, makes them attractive contributors to establishing complete viral defense methods for upcoming epidemics.
Khatti J., Muhmed A., Grover K.S.
Earth Science Informatics scimago Q2 wos Q2
2025-02-05 citations by CoLab: 0 Abstract  
Expansive soils pose significant challenges due to their tendency to swell when wet and shrink when dry, causing ground instability. These volumetric changes can lead to structural damage, including foundation cracks, uneven floors, and compromised infrastructure. Addressing these issues requires proper soil evaluation and the implementation of stabilization techniques to ensure long-term safety and durability. The high degree of expansive, problematic soil is stabilized by cement, bitumen, lime, etc. This investigation predicts the unconfined compressive strength (UCS) of lime-treated soil using decision tree (DT), ensemble tree (ET), gaussian process regression (GPR), support vector machine (SVM), and multilinear regression (MLR). This research investigates the impact of dimensionality on the computational approaches. The variance accounted for (VAF), correlation coefficient (R), mean absolute error (MAE), root mean square error (RMSE), and performance index (PI) metrics have computed the model's performance. The comparison reveals that model ET5 has predicted UCS with an excellent performance in testing (RMSE = 368.06 kPa, R = 0.9640, VAF = 91.60, PI = 1.8077) and validation (RMSE = 508.41 kPa, R = 0.9165, VAF = 83.89, PI = 1.6337) phase. Also, model ET5 has achieved better score (total = 90), area over the curve (testing = 8.98E-04, validation = 1.56E-03), computational cost (testing = 0.1772s, validation = 0.1551 s), uncertainty rank (= 1), and overfitting (testing = 2.32, validation = 2.80), presenting model ET5 as an optimal performance model. The dimensionality analysis reveals that simple models like MLR, SVM, GPR, and DT struggle with high-dimensional data (case 5). Still, the ET5 model achieves high performance and reliable prediction with consistency, compaction and soil physical parameters. Conversely, the effect of multicollinearity has been observed on the performance of the MLR, SVM, and DT models.
Hussain A., Hussain A.
2025-02-03 citations by CoLab: 0 Abstract  
The Monkeypox virus (MPXV) has recently been identified as a new global health concern and, as such, requires new therapeutic approaches. Small molecules that can selfassemble into micelles have been demonstrated to improve solubility, pharmacokinetics, and antiviral activity. Latest results suggest that amphiphilic small molecules enhance drug delivery and, importantly, can disrupt virus envelopes, which is required for MPXV. Moreover, encapsulating amphiphilic antiviral molecules with various hydrophobic drugs will significantly enhance their therapeutic indexes. This article presents a computational strategy based on molecular docking, dynamics simulations, and drug-mate nano assembly technologies in high antiviral efficiency against MPXV. This study, in fact, proposes new pathways for developing antiviral agents through the identification of key viral proteins as targets and based on insights obtained from already existing research. Safety considerations of amphiphilic molecules in humans have also been discussed. To this end, and through the identification of key viral proteins and the application of drug design principles, we hope to progress the development of novel antiviral agents and potential treatment strategies for MPXV.
Vashist M., Singh S.K., Kumar T.V.
Biodiversity and Conservation scimago Q1 wos Q2
2025-02-02 citations by CoLab: 1 Abstract  
Urban trees provide essential provisioning, regulating, and cultural services, such as carbon sequestration, air and water quality regulation, and pest and disease control. However, unregulated urbanization increases the vulnerability of these trees to invasive pests, leading to tree loss and a reduction in ecosystem benefits. While many studies focus on forest ecosystems, limited research exists on the impact of pests and disease in urban settings. This review aims to address this gap by examining the ecosystem services provided by urban trees and the threats posed by pests and pathogens on them. It highlights the negative implications of pests on urban trees, affecting ecological, economic, and cultural factors such as disrupting biodiversity, reducing ecosystem services, increasing management costs, lowering property values, degrading aesthetics and heritage value, and risking human health. It discusses several strategies to mitigate the adverse effects of pests and pathogens and control their spread. Additionally, it characterizes the various stages to detect and manage tree pests (pre-border, border, or post-border) and identifies critical areas for further improvements within each stage before their establishment. The study also highlights strategies like biological control and implementing well-designed landscapes (with high diversity street trees), which can effectively control the spread and mitigate the pests after their establishment. In conclusion, the study emphasizes that effective pest management requires revising existing laws and policies at various administrative levels, necessitating a collaborative and inclusive approach that involves multiple stakeholders, local actors, and the public in creating sustainable and resilient urban environments.
Shringi S., Acharya B.
2025-02-01 citations by CoLab: 0 Abstract  
Soft deposits are typically extremely compressible subsoil features, such as uncontrolled settlement brought on by subsoil failure of bearing capacity. The drawback of building on soft ground is that it might instantly drive-up construction costs. On soft soil, geosynthetics have been used more frequently as reinforcement in road embankments but even after the construction of the embankment, settlement takes place. In order to mitigate settlement issues in embankments, the incorporation of a geosynthetic product within the soft ground is essential. The computational framework chosen for this study enables the creation of diverse soil models. However, to replicate the characteristics of the soft soil and embankment fill accurately, the Mohr–Coulomb model, known for its simplicity, practical significance, and availability of requisite data, is employed. This particular model is widely embraced by geotechnical engineering practitioners. It facilitated the execution of numerical simulations based on both geotechnical research and on-site observations. The primary aim of this review article is to provide an overview of geosynthetic material’s utilization for reinforcing road embankments constructed over soft soil conditions.
Saini R., Acharya B.
2025-02-01 citations by CoLab: 0 Abstract  
This review delves into the behaviour of stone columns, a prominent ground improvement technique, using the finite element method (FEM) with the PLAXIS 2D software. The study entails a thorough examination of stone column performance, considering various factors that influence their behaviour within the context of layered soil systems. Through a detailed literature analysis, this review aims to provide insights into the effectiveness of stone columns (SC) in enhancing soil load-bearing capacity and reducing differential settlement. The review contributes to a better understanding of the applicability and performance of SC as a solution for soil reinforcement.
Sharma S., Bindlish A.
2025-02-01 citations by CoLab: 0 Abstract  
Numerous additive materials have been used in the geotechnical engineering field for enhancement as well to improve the soil’s properties. Recently, polymeric-based stabilizers have shown the importance and are rapidly increasing in demand for stabilization of the soil. A long chain of polymers known as a polyacrylamide (PAM) seek its attention as it is easily soluble in water, more comfortable and effective. These additives showed up a superiority over traditional stabilizers. PAM can be used in pavement of the roads, helpful in prevention of soil erosion, and in construction, it is very cost effective. Basically, our aim is to give a review on the latest research or findings of these polymers-based additives and advancement in the PAM work. PAM is very commonly used polymer and works on the principle of the floc formation with the particle interaction of the soil.
Kumar P., Choudhary M.P., Mathur A.K.
2025-01-30 citations by CoLab: 0 Abstract  
The current study investigates the relationship between urbanization, solid waste generation, and environmental changes in Kota city from 2000 to 2023. The study employs Google Earth Engine (GEE) to analyze land use and land cover (LULC) classification, normalized difference vegetation index (NDVI), normalized difference modified water index (NDMWI), normalized difference built-up index (NDBI), land surface temperature (LST), and predict future LULC changes up to 2043. The results show that the built-up area increased by 122.38%, correlated with a 294.16% increase in solid waste generation and a significant increase of 24.6% in urban temperature (R2 = 0.9936). Vegetation cover and water resources declined during this period, and NDVI and NDMWI values indicate environmental degradation. Future LULC forecasts for 2043 show that urban expansion will continue, with built-up areas expected to increase by 16.74% at the expense of natural resources. To mitigate these effects, the study emphasizes the need for sustainable urban planning, which includes green infrastructure, advanced waste recycling systems, and strategies to mitigate urban heat islands. These findings provide significant insights for policymakers who seek to balance urban growth with environmental sustainability and proficient waste management.
Chammam W., Rathie A.K., Khlifi M.
Afrika Matematika scimago Q3 wos Q2 Open Access
2025-01-21 citations by CoLab: 0 PDF Abstract  
In this paper, first we present two new integral representations of the Gauss hypergeometric function in the form of double integrals obtained recently by us Chammam et al. (Bull Belgian Math Soc 31(3), 336–340, 2024). Two specific cases of our representations allow for an alternative proofs of the well-known Gauss summation theorem and Watson summation theorem. Additionally, as an application, we introduce a new class of double integrals and provide interesting integral representations for Catalan–Qi numbers and Fuss–Catalan–Qi numbers.
Hussain A., Hussain A.
2025-01-14 citations by CoLab: 0 Abstract  
Donanemab is the first antibody to target pyroglutamate-modified amyloid-beta in Alzheimer's disease selectively; thus, it represents a significant breakthrough in disease-modifying treatments. Importantly, its mechanism of action encourages adequate clearance of plaques and does not even worsen outcomes for early-stage patients, in contrast to previous treatments that did not promote clearing for plaques or even worsened the outcomes of early-stage patients. The integration of quantum computing in drug discovery holds tremendous transformations in terms of enhancing the therapeutic approach against Alzheimer's disease. Researchers can speed up discovering novel compounds, optimize treatment regimens, and personalize patient care according to individual neurobiological profiles by using quantum computing powers. The letter to the editor discusses the unique attributes of Donanemab, its clinical superiority, and the related side effects, besides pushing for the promising future of integrating quantum computing into the paradigms of Alzheimer's treatment. Though promising, integrating quantum computing into medical practice is challenged by factors such as high computational costs, data privacy, and ethical considerations that must be taken within strict regulatory frameworks.
Hussain A., Hussain A.
2025-01-14 citations by CoLab: 0 Abstract  
In the last few years, there have been significant advances in cancer agent research, most of which entered clinical trials after succeeding in initial preclinical studies. Here, we discuss successful accomplishments in the promising approaches of targeted therapies, immunotherapies, and combination therapies. The development in these areas includes sotorasib - targeting the mutation of KRAS for lung and pancreatic cancer and pembrolizumab - an immune checkpoint inhibitor for melanoma therapy; the latter has been synergistic with chemotherapy. In addition, exciting results emerge from trials with the DNA damage repair inhibitor olaparib in BRCA-mutated cancers and the tyrosine kinase inhibitor osimertinib for EGFR-mutant lung cancer. Bevacizumab continues to establish itself as an evolving therapy in colorectal cancer, and niraparib enters Phase III in ovarian cancer. New combinations will include alpelisib and PD-1 inhibitors and nanoparticle-based Abraxane for triple-negative breast cancers leading toward precision medicine. These would improve the survival rates and quality of life in patients with advanced or refractory malignancies.
Trikha A., Saini K.
2025-01-10 citations by CoLab: 0 Abstract  
Sharenting happens when parents or relatives post photos of their children, usually minors, on social media. However, this has privacy-compromising and child-risking consequences, which may lead to cyber fraud. The paper aims to validate a digital parental sharing scale (DPSS) in the Indian Context. A proper process of designing and validating the scale was carried out on a sample of 250 Indian parents. With the help of analytical tools, the validity and reliability of the analysis were validated. A fourteen-item scale was validated based on social acceptance, Privacy and control, Memories and milestones, and Cyber Security. With good psychometric properties, the scale is validated as a reliable instrument for recording the level of sharenting amongst Indian Parents. The research paper is limited to understanding the level of sharenting by Indian parents. It has not explored the effects of sharenting on Indian children.

Since 2008

Total publications
915
Total citations
7551
Citations per publication
8.25
Average publications per year
53.82
Average authors per publication
3.26
h-index
38
Metrics description

Top-30

Fields of science

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Electrical and Electronic Engineering, 112, 12.24%
General Medicine, 66, 7.21%
General Mathematics, 49, 5.36%
Applied Mathematics, 47, 5.14%
Computer Science Applications, 44, 4.81%
Renewable Energy, Sustainability and the Environment, 41, 4.48%
General Materials Science, 40, 4.37%
General Engineering, 36, 3.93%
Mechanical Engineering, 35, 3.83%
Energy Engineering and Power Technology, 34, 3.72%
Electronic, Optical and Magnetic Materials, 29, 3.17%
Condensed Matter Physics, 28, 3.06%
Computer Networks and Communications, 27, 2.95%
Analysis, 26, 2.84%
Hardware and Architecture, 24, 2.62%
Civil and Structural Engineering, 24, 2.62%
Software, 23, 2.51%
Geotechnical Engineering and Engineering Geology, 23, 2.51%
Artificial Intelligence, 22, 2.4%
General Computer Science, 22, 2.4%
Industrial and Manufacturing Engineering, 21, 2.3%
Mechanics of Materials, 21, 2.3%
Modeling and Simulation, 20, 2.19%
Information Systems, 17, 1.86%
Theoretical Computer Science, 17, 1.86%
Algebra and Number Theory, 17, 1.86%
General Physics and Astronomy, 16, 1.75%
Pollution, 16, 1.75%
Building and Construction, 16, 1.75%
Control and Systems Engineering, 15, 1.64%
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With other organizations

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With foreign organizations

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With other countries

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Ethiopia, 50, 5.46%
Saudi Arabia, 32, 3.5%
Lebanon, 18, 1.97%
Republic of Korea, 17, 1.86%
Turkey, 16, 1.75%
Romania, 13, 1.42%
China, 12, 1.31%
United Kingdom, 9, 0.98%
USA, 8, 0.87%
Germany, 7, 0.77%
Australia, 7, 0.77%
Singapore, 7, 0.77%
Egypt, 6, 0.66%
UAE, 6, 0.66%
Malaysia, 5, 0.55%
Nigeria, 5, 0.55%
Oman, 5, 0.55%
Japan, 5, 0.55%
Vietnam, 4, 0.44%
Slovenia, 4, 0.44%
South Africa, 4, 0.44%
Pakistan, 3, 0.33%
Serbia, 3, 0.33%
Brazil, 2, 0.22%
Jordan, 2, 0.22%
Iran, 2, 0.22%
Italy, 2, 0.22%
New Zealand, 2, 0.22%
Poland, 2, 0.22%
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  • We do not take into account publications without a DOI.
  • Statistics recalculated daily.
  • Publications published earlier than 2008 are ignored in the statistics.
  • The horizontal charts show the 30 top positions.
  • Journals quartiles values are relevant at the moment.