Phytotherapy Research, volume 14, issue 3, pages 160-162
Dihydroquercetin as a means of antioxidative defence in rats with tetrachloromethane hepatitis
Teselkin Yu O
1
,
Babenkova I V
1
,
Kolhir V K
2
,
Baginskaya A I
2
,
Tjukavkina N A
3
,
Kolesnik Yu A
3
,
Selivanova I A
3
,
Eichholz A A
4
2
Department of Medicine, Institute of Plant Substances, Grin Street 7, Moscow 113628, Russia
|
3
Department of Organic Chemistry, Moscow Medical Academy, 5th Parkovaya Street 21, Moscow 105043, Russia
|
4
Department of Physiology and Biophysics, UMDNJ‐Johnson Medical School, P.O. Box 431, Tracys Landing, MD 20779, USA
|
Publication type: Journal Article
Publication date: 2000-05-01
Journal:
Phytotherapy Research
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 7.2
ISSN: 0951418X, 10991573
Pharmacology
Abstract
The antioxidant effect of dihydroquercetin (DHQ) was studied in Wistar rats with experimental hepatitis, caused by tetrachloromethane (CCl(4)). Animals were divided into three groups: intact (n = 9); control (n = 9) which received CCl(4) subcutaneously for 4 days (4 mL/kg); and experimental (n = 9) which received DHQ (100 mg/kg) for 4 days prior to the first administration of CCl(4) and during the course of the subsequent 14 days. DHQ was intubated per os, using a water crystalline suspension. The content of products of lipid peroxidation, reacting with thiobarbituric acid in the serum and liver of the control animals, was increased by more than 1.5 fold compared with the intact and experimental animals (p < 0.01). The blood plasma antioxidant activity of the control animals was 1.8 to 2 times lower than that of experimental and intact animals (p < 0.01) It is suggested that the data obtained are dependent on the anti-oxidant properties of DHQ.
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Hindawi Limited
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5
10
15
20
25
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- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
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Teselkin Yu. O. et al. Dihydroquercetin as a means of antioxidative defence in rats with tetrachloromethane hepatitis // Phytotherapy Research. 2000. Vol. 14. No. 3. pp. 160-162.
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Teselkin Yu. O., Babenkova I. V., Kolhir V. K., Baginskaya A. I., Tjukavkina N. A., Kolesnik Yu. A., Selivanova I. A., Eichholz A. A. Dihydroquercetin as a means of antioxidative defence in rats with tetrachloromethane hepatitis // Phytotherapy Research. 2000. Vol. 14. No. 3. pp. 160-162.
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TY - JOUR
DO - 10.1002/(sici)1099-1573(200005)14:3<160::aid-ptr555>3.0.co;2-y
UR - https://doi.org/10.1002%2F%28sici%291099-1573%28200005%2914%3A3%3C160%3A%3Aaid-ptr555%3E3.0.co%3B2-y
TI - Dihydroquercetin as a means of antioxidative defence in rats with tetrachloromethane hepatitis
T2 - Phytotherapy Research
AU - Teselkin, Yu O
AU - Babenkova, I V
AU - Kolhir, V K
AU - Baginskaya, A I
AU - Tjukavkina, N A
AU - Kolesnik, Yu A
AU - Selivanova, I A
AU - Eichholz, A A
PY - 2000
DA - 2000/05/01 00:00:00
PB - Wiley
SP - 160-162
IS - 3
VL - 14
SN - 0951-418X
SN - 1099-1573
ER -
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@article{2000_Teselkin,
author = {Yu O Teselkin and I V Babenkova and V K Kolhir and A I Baginskaya and N A Tjukavkina and Yu A Kolesnik and I A Selivanova and A A Eichholz},
title = {Dihydroquercetin as a means of antioxidative defence in rats with tetrachloromethane hepatitis},
journal = {Phytotherapy Research},
year = {2000},
volume = {14},
publisher = {Wiley},
month = {may},
url = {https://doi.org/10.1002%2F%28sici%291099-1573%28200005%2914%3A3%3C160%3A%3Aaid-ptr555%3E3.0.co%3B2-y},
number = {3},
pages = {160--162},
doi = {10.1002/(sici)1099-1573(200005)14:3<160::aid-ptr555>3.0.co;2-y}
}
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Teselkin, Yu. O., et al. “Dihydroquercetin as a means of antioxidative defence in rats with tetrachloromethane hepatitis.” Phytotherapy Research, vol. 14, no. 3, May. 2000, pp. 160-162. https://doi.org/10.1002%2F%28sici%291099-1573%28200005%2914%3A3%3C160%3A%3Aaid-ptr555%3E3.0.co%3B2-y.
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