Sulfonyl Fluoride Analogues as Activity-Based Probes for Serine Proteases
D. Alexander Shannon
1
,
Christian Gu
2
,
Christopher J. McLaughlin
1
,
Markus Kaiser
3
,
Renier AL van der Hoorn
2
,
Eranthie Weerapana
1
Publication type: Journal Article
Publication date: 2012-09-24
scimago Q1
wos Q3
SJR: 0.844
CiteScore: 5.2
Impact factor: 2.8
ISSN: 14394227, 14397633
PubMed ID:
23008217
Organic Chemistry
Biochemistry
Molecular Biology
Molecular Medicine
Abstract
Enriched with fluoride: To expand on the available tools to interrogate proteases, we explored sulfonyl fluorides as activity-based probes. An alkyne-tagged sulfonyl fluoride covalently modifies members of the S1 family of serine proteases. By applying click chemistry, avidin enrichment and mass spectrometry, we can enrich and identify active endogenous serine proteases from a complex proteome.
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Metrics
77
Total citations:
77
Citations from 2024:
12
(15%)
Cite this
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RIS |
BibTex |
MLA
Cite this
GOST
Copy
Shannon D. A. et al. Sulfonyl Fluoride Analogues as Activity-Based Probes for Serine Proteases // ChemBioChem. 2012. Vol. 13. No. 16. pp. 2327-2330.
GOST all authors (up to 50)
Copy
Shannon D. A., Gu C., McLaughlin C. J., Kaiser M., van der Hoorn R. A., Weerapana E. Sulfonyl Fluoride Analogues as Activity-Based Probes for Serine Proteases // ChemBioChem. 2012. Vol. 13. No. 16. pp. 2327-2330.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1002/cbic.201200531
UR - https://doi.org/10.1002/cbic.201200531
TI - Sulfonyl Fluoride Analogues as Activity-Based Probes for Serine Proteases
T2 - ChemBioChem
AU - Shannon, D. Alexander
AU - Gu, Christian
AU - McLaughlin, Christopher J.
AU - Kaiser, Markus
AU - van der Hoorn, Renier AL
AU - Weerapana, Eranthie
PY - 2012
DA - 2012/09/24
PB - Wiley
SP - 2327-2330
IS - 16
VL - 13
PMID - 23008217
SN - 1439-4227
SN - 1439-7633
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2012_Shannon,
author = {D. Alexander Shannon and Christian Gu and Christopher J. McLaughlin and Markus Kaiser and Renier AL van der Hoorn and Eranthie Weerapana},
title = {Sulfonyl Fluoride Analogues as Activity-Based Probes for Serine Proteases},
journal = {ChemBioChem},
year = {2012},
volume = {13},
publisher = {Wiley},
month = {sep},
url = {https://doi.org/10.1002/cbic.201200531},
number = {16},
pages = {2327--2330},
doi = {10.1002/cbic.201200531}
}
Cite this
MLA
Copy
Shannon, D. Alexander, et al. “Sulfonyl Fluoride Analogues as Activity-Based Probes for Serine Proteases.” ChemBioChem, vol. 13, no. 16, Sep. 2012, pp. 2327-2330. https://doi.org/10.1002/cbic.201200531.