Chemical Record, volume 16, issue 3, pages 1578-1590

Extending the Substrate Scope for the Asymmetric Iridium-Catalyzed Hydrogenation of Minimally Functionalized Olefins by Using Biaryl Phosphite-Based Modular Ligand Libraries

Publication type: Journal Article
Publication date: 2016-05-27
Journal: Chemical Record
scimago Q1
SJR: 1.338
CiteScore: 11.0
Impact factor: 7
ISSN: 15278999, 15280691
Materials Chemistry
General Chemistry
Biochemistry
General Chemical Engineering
Abstract
Asymmetric hydrogenation is one of the most efficient and atom-economical tools to prepare chiral molecules. However, the enantiodiscrimination of simple, minimally functionalized olefins is still challenging and requires more sophisticated ligand design. Herein, we discuss our progress in the successful development of ligand design for the iridium-catalyzed asymmetric hydrogenation of minimally functionalized olefins.
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