Double‐Oxidative Dehydrogenative (DOD) Cyclization of Glycine Derivatives with Dioxane under Metal‐Free Aerobic Conditions
Publication type: Journal Article
Publication date: 2016-02-15
scimago Q1
wos Q1
SJR: 0.930
CiteScore: 8.0
Impact factor: 4.0
ISSN: 16154150, 16154169
General Chemistry
Abstract
The first carbon tetrabromide-promoted novel double-oxidative dehydrogenative cyclization/acidic ring opening/aromatization tandem reaction of glycine derivatives with dioxane for the synthesis of complex quinoline motifs has been developed (up to 71% yield). The use of very inexpensive substrates (glycine derivatives and dioxane) and an extremely simple metal-free promoter (carbon tetrabromide) with green molecular oxygen (air) as an oxidant make this protocol very attractive for potential synthetic applications. A plausible mechanism involving a radical process is proposed.
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Metrics
55
Total citations:
55
Citations from 2025:
2
(3.64%)
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MLA
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GOST
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Huo C. et al. Double‐Oxidative Dehydrogenative (DOD) Cyclization of Glycine Derivatives with Dioxane under Metal‐Free Aerobic Conditions // Advanced Synthesis and Catalysis. 2016. Vol. 358. No. 5. pp. 724-730.
GOST all authors (up to 50)
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Huo C., Xie H., Chen F., Tang J., Wang Y. Double‐Oxidative Dehydrogenative (DOD) Cyclization of Glycine Derivatives with Dioxane under Metal‐Free Aerobic Conditions // Advanced Synthesis and Catalysis. 2016. Vol. 358. No. 5. pp. 724-730.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1002/adsc.201500893
UR - https://doi.org/10.1002/adsc.201500893
TI - Double‐Oxidative Dehydrogenative (DOD) Cyclization of Glycine Derivatives with Dioxane under Metal‐Free Aerobic Conditions
T2 - Advanced Synthesis and Catalysis
AU - Huo, Congde
AU - Xie, Haisheng
AU - Chen, Fengjuan
AU - Tang, Jing
AU - Wang, Yajun
PY - 2016
DA - 2016/02/15
PB - Wiley
SP - 724-730
IS - 5
VL - 358
SN - 1615-4150
SN - 1615-4169
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2016_Huo,
author = {Congde Huo and Haisheng Xie and Fengjuan Chen and Jing Tang and Yajun Wang},
title = {Double‐Oxidative Dehydrogenative (DOD) Cyclization of Glycine Derivatives with Dioxane under Metal‐Free Aerobic Conditions},
journal = {Advanced Synthesis and Catalysis},
year = {2016},
volume = {358},
publisher = {Wiley},
month = {feb},
url = {https://doi.org/10.1002/adsc.201500893},
number = {5},
pages = {724--730},
doi = {10.1002/adsc.201500893}
}
Cite this
MLA
Copy
Huo, Congde, et al. “Double‐Oxidative Dehydrogenative (DOD) Cyclization of Glycine Derivatives with Dioxane under Metal‐Free Aerobic Conditions.” Advanced Synthesis and Catalysis, vol. 358, no. 5, Feb. 2016, pp. 724-730. https://doi.org/10.1002/adsc.201500893.