volume 48 issue 34 pages 6324-6327

Catalytic Enantioselective Trifluoromethylation of Azomethine Imines with Trimethyl(trifluoromethyl)silane

Hiroyuki Kawai 1
Akihiro Kusuda 1
Shuichi NAKAMURA 1
Motoo Shiro 2
Publication typeJournal Article
Publication date2009-07-15
scimago Q1
wos Q1
SJR5.550
CiteScore27.6
Impact factor16.9
ISSN14337851, 15213773
General Chemistry
Catalysis
Abstract
It′s a cinch! The title reaction with azomethine imines 1 uses an operationally simple procedure, based on the combination of the bromide salt of cinchona alkaloids (3) and KOH. The procedure is reliable and general. Trifluoromethyl-substituted amines can be accessed by a two-step deprotection of the product (S)-2.
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GOST Copy
Kawai H. et al. Catalytic Enantioselective Trifluoromethylation of Azomethine Imines with Trimethyl(trifluoromethyl)silane // Angewandte Chemie - International Edition. 2009. Vol. 48. No. 34. pp. 6324-6327.
GOST all authors (up to 50) Copy
Kawai H., Kusuda A., NAKAMURA S., Shiro M., Shibata N. Catalytic Enantioselective Trifluoromethylation of Azomethine Imines with Trimethyl(trifluoromethyl)silane // Angewandte Chemie - International Edition. 2009. Vol. 48. No. 34. pp. 6324-6327.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1002/anie.200902457
UR - https://doi.org/10.1002/anie.200902457
TI - Catalytic Enantioselective Trifluoromethylation of Azomethine Imines with Trimethyl(trifluoromethyl)silane
T2 - Angewandte Chemie - International Edition
AU - Kawai, Hiroyuki
AU - Kusuda, Akihiro
AU - NAKAMURA, Shuichi
AU - Shiro, Motoo
AU - Shibata, Norio
PY - 2009
DA - 2009/07/15
PB - Wiley
SP - 6324-6327
IS - 34
VL - 48
PMID - 19606438
SN - 1433-7851
SN - 1521-3773
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2009_Kawai,
author = {Hiroyuki Kawai and Akihiro Kusuda and Shuichi NAKAMURA and Motoo Shiro and Norio Shibata},
title = {Catalytic Enantioselective Trifluoromethylation of Azomethine Imines with Trimethyl(trifluoromethyl)silane},
journal = {Angewandte Chemie - International Edition},
year = {2009},
volume = {48},
publisher = {Wiley},
month = {jul},
url = {https://doi.org/10.1002/anie.200902457},
number = {34},
pages = {6324--6327},
doi = {10.1002/anie.200902457}
}
MLA
Cite this
MLA Copy
Kawai, Hiroyuki, et al. “Catalytic Enantioselective Trifluoromethylation of Azomethine Imines with Trimethyl(trifluoromethyl)silane.” Angewandte Chemie - International Edition, vol. 48, no. 34, Jul. 2009, pp. 6324-6327. https://doi.org/10.1002/anie.200902457.