Angewandte Chemie - International Edition, volume 58, issue 2, pages 390-402
Transition-Metal-Mediated and -Catalyzed C−F Bond Activation by Fluorine Elimination
Publication type: Journal Article
Publication date: 2018-11-08
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 16.6
ISSN: 14337851, 15213773
General Chemistry
Catalysis
Abstract
The activation of carbon-fluorine (C-F) bonds is an important topic in synthetic organic chemistry. Metal-mediated and -catalyzed elimination of β- or α-fluorine proceeds under milder conditions than oxidative addition to C-F bonds. The β- or α-fluorine elimination is initiated from organometallic intermediates having fluorine substituents on carbon atoms β or α to metal centers, respectively. Transformations through these elimination processes (C-F bond cleavage), which are typically preceded by carbon-carbon (or carbon-heteroatom) bond formation, have been increasingly developed in the past five years as C-F bond activation methods. In this Minireview, we summarize the applications of transition-metal-mediated and -catalyzed fluorine elimination to synthetic organic chemistry from a historical perspective with early studies and from a systematic perspective with recent studies.
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Fujita T., Fuchibe K., Ichikawa J. Transition-Metal-Mediated and -Catalyzed C−F Bond Activation by Fluorine Elimination // Angewandte Chemie - International Edition. 2018. Vol. 58. No. 2. pp. 390-402.
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Fujita T., Fuchibe K., Ichikawa J. Transition-Metal-Mediated and -Catalyzed C−F Bond Activation by Fluorine Elimination // Angewandte Chemie - International Edition. 2018. Vol. 58. No. 2. pp. 390-402.
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TY - JOUR
DO - 10.1002/anie.201805292
UR - https://doi.org/10.1002/anie.201805292
TI - Transition-Metal-Mediated and -Catalyzed C−F Bond Activation by Fluorine Elimination
T2 - Angewandte Chemie - International Edition
AU - Fuchibe, Kohei
AU - Fujita, Takeshi
AU - Ichikawa, J.
PY - 2018
DA - 2018/11/08 00:00:00
PB - Wiley
SP - 390-402
IS - 2
VL - 58
SN - 1433-7851
SN - 1521-3773
ER -
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@article{2018_Fujita,
author = {Kohei Fuchibe and Takeshi Fujita and J. Ichikawa},
title = {Transition-Metal-Mediated and -Catalyzed C−F Bond Activation by Fluorine Elimination},
journal = {Angewandte Chemie - International Edition},
year = {2018},
volume = {58},
publisher = {Wiley},
month = {nov},
url = {https://doi.org/10.1002/anie.201805292},
number = {2},
pages = {390--402},
doi = {10.1002/anie.201805292}
}
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Fujita, Takeshi, et al. “Transition-Metal-Mediated and -Catalyzed C−F Bond Activation by Fluorine Elimination.” Angewandte Chemie - International Edition, vol. 58, no. 2, Nov. 2018, pp. 390-402. https://doi.org/10.1002/anie.201805292.