The Buchwald–Hartwig Amination After 25 Years
3
Department for Intermediates—Amine SynthesisBASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Germany
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Publication type: Journal Article
Publication date: 2019-11-25
scimago Q1
wos Q1
SJR: 5.550
CiteScore: 27.6
Impact factor: 16.9
ISSN: 14337851, 15213773
PubMed ID:
31166642
General Chemistry
Catalysis
Abstract
The Pd-catalyzed coupling of aryl (pseudo)halides and amines is one of the most powerful approaches for the formation of C(sp2 )-N bonds. The pioneering reports from Migita and subsequently Buchwald and Hartwig on the coupling of aminostannanes and aryl bromides rapidly evolved into general and practical tin-free protocols with broad substrate scope, which led to the establishment of what is now known as the Buchwald-Hartwig amination. This Minireview summarizes the evolution of this cross-coupling reaction over the course of the past 25 years and illustrates some of the most recent applications of this well-established methodology.
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542
Total citations:
542
Citations from 2024:
201
(37.09%)
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GOST
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Dorel R., Grugel C. P., Haydl A. M. The Buchwald–Hartwig Amination After 25 Years // Angewandte Chemie - International Edition. 2019. Vol. 58. No. 48. pp. 17118-17129.
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Dorel R., Grugel C. P., Haydl A. M. The Buchwald–Hartwig Amination After 25 Years // Angewandte Chemie - International Edition. 2019. Vol. 58. No. 48. pp. 17118-17129.
Cite this
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TY - JOUR
DO - 10.1002/anie.201904795
UR - https://doi.org/10.1002/anie.201904795
TI - The Buchwald–Hartwig Amination After 25 Years
T2 - Angewandte Chemie - International Edition
AU - Dorel, Ruth
AU - Grugel, Christian P
AU - Haydl, Alexander M
PY - 2019
DA - 2019/11/25
PB - Wiley
SP - 17118-17129
IS - 48
VL - 58
PMID - 31166642
SN - 1433-7851
SN - 1521-3773
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2019_Dorel,
author = {Ruth Dorel and Christian P Grugel and Alexander M Haydl},
title = {The Buchwald–Hartwig Amination After 25 Years},
journal = {Angewandte Chemie - International Edition},
year = {2019},
volume = {58},
publisher = {Wiley},
month = {nov},
url = {https://doi.org/10.1002/anie.201904795},
number = {48},
pages = {17118--17129},
doi = {10.1002/anie.201904795}
}
Cite this
MLA
Copy
Dorel, Ruth, et al. “The Buchwald–Hartwig Amination After 25 Years.” Angewandte Chemie - International Edition, vol. 58, no. 48, Nov. 2019, pp. 17118-17129. https://doi.org/10.1002/anie.201904795.