Parahydrogen Hyperpolarization Allows Direct NMR Detection of α‐Amino Acids in Complex (Bio)mixtures
Publication type: Journal Article
Publication date: 2021-11-18
scimago Q1
wos Q1
SJR: 5.550
CiteScore: 27.6
Impact factor: 16.9
ISSN: 14337851, 15213773
PubMed ID:
34534406
General Chemistry
Catalysis
Abstract
Non-hydrogenative parahydrogen hyperpolarization allows the detection and quantification of α-amino acids down to sub-micromolar concentrations. This method can also be applied to aqueous mixtures after dilution with methanol without any additional sample treatment. This direct approach was tested on human urine, allowing a well-resolved detection of amino acids despite the complexity of the mixture.
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41
Total citations:
41
Citations from 2025:
10
(25%)
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GOST
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Sellies L. et al. Parahydrogen Hyperpolarization Allows Direct NMR Detection of α‐Amino Acids in Complex (Bio)mixtures // Angewandte Chemie - International Edition. 2021. Vol. 60. No. 52. pp. 26954-26959.
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Sellies L., Aspers R. L. E. G., Feiters M., Rutjes F. P. J. T., Tessari M. Parahydrogen Hyperpolarization Allows Direct NMR Detection of α‐Amino Acids in Complex (Bio)mixtures // Angewandte Chemie - International Edition. 2021. Vol. 60. No. 52. pp. 26954-26959.
Cite this
RIS
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TY - JOUR
DO - 10.1002/anie.202109588
UR - https://doi.org/10.1002/anie.202109588
TI - Parahydrogen Hyperpolarization Allows Direct NMR Detection of α‐Amino Acids in Complex (Bio)mixtures
T2 - Angewandte Chemie - International Edition
AU - Sellies, Lisanne
AU - Aspers, Ruud L. E. G.
AU - Feiters, Martin
AU - Rutjes, Floris P. J. T.
AU - Tessari, M.
PY - 2021
DA - 2021/11/18
PB - Wiley
SP - 26954-26959
IS - 52
VL - 60
PMID - 34534406
SN - 1433-7851
SN - 1521-3773
ER -
Cite this
BibTex (up to 50 authors)
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@article{2021_Sellies,
author = {Lisanne Sellies and Ruud L. E. G. Aspers and Martin Feiters and Floris P. J. T. Rutjes and M. Tessari},
title = {Parahydrogen Hyperpolarization Allows Direct NMR Detection of α‐Amino Acids in Complex (Bio)mixtures},
journal = {Angewandte Chemie - International Edition},
year = {2021},
volume = {60},
publisher = {Wiley},
month = {nov},
url = {https://doi.org/10.1002/anie.202109588},
number = {52},
pages = {26954--26959},
doi = {10.1002/anie.202109588}
}
Cite this
MLA
Copy
Sellies, Lisanne, et al. “Parahydrogen Hyperpolarization Allows Direct NMR Detection of α‐Amino Acids in Complex (Bio)mixtures.” Angewandte Chemie - International Edition, vol. 60, no. 52, Nov. 2021, pp. 26954-26959. https://doi.org/10.1002/anie.202109588.