volume 354 issue 1 pages 2000163

1,2,3‐Triazole hybrids with anti‐HIV‐1 activity

Lian Shun Feng 1
Man Jie Zheng 1
Feng Zhao 1
Duan Liu 1
Publication typeJournal Article
Publication date2020-09-22
scimago Q2
wos Q2
SJR0.571
CiteScore7.0
Impact factor3.6
ISSN03656233, 15214184
Drug Discovery
Pharmaceutical Science
Abstract
The human immunodeficiency virus type 1 (HIV-1) is the major etiological agent responsible for the acquired immunodeficiency syndrome (AIDS), which is a serious infectious disease and remains one of the most prevalent problems at present. Currently, combined antiretroviral therapy is the primary modality for the treatment and management of HIV/AIDS, but the long-term use can result in major drawbacks such as the development of multidrug-resistant viruses and multiple side effects. 1,2,3-Triazole is the common framework in the development of new drugs, and its derivatives have the potential to inhibit various HIV-1 enzymes such as reverse transcriptase, integrase, and protease, consequently possessing a potential anti-HIV-1 activity. This review covers the recent advances regarding the 1,2,3-triazole hybrids with potential anti-HIV-1 activity; it focuses on the chemical structures, structure-activity relationship, and mechanisms of action, covering articles published from 2010 to 2020.
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GOST |
Cite this
GOST Copy
Feng L. S. et al. 1,2,3‐Triazole hybrids with anti‐HIV‐1 activity // Archiv der Pharmazie. 2020. Vol. 354. No. 1. p. 2000163.
GOST all authors (up to 50) Copy
Feng L. S., Zheng M. J., Zhao F., Liu D. 1,2,3‐Triazole hybrids with anti‐HIV‐1 activity // Archiv der Pharmazie. 2020. Vol. 354. No. 1. p. 2000163.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1002/ardp.202000163
UR - https://doi.org/10.1002/ardp.202000163
TI - 1,2,3‐Triazole hybrids with anti‐HIV‐1 activity
T2 - Archiv der Pharmazie
AU - Feng, Lian Shun
AU - Zheng, Man Jie
AU - Zhao, Feng
AU - Liu, Duan
PY - 2020
DA - 2020/09/22
PB - Wiley
SP - 2000163
IS - 1
VL - 354
PMID - 32960467
SN - 0365-6233
SN - 1521-4184
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2020_Feng,
author = {Lian Shun Feng and Man Jie Zheng and Feng Zhao and Duan Liu},
title = {1,2,3‐Triazole hybrids with anti‐HIV‐1 activity},
journal = {Archiv der Pharmazie},
year = {2020},
volume = {354},
publisher = {Wiley},
month = {sep},
url = {https://doi.org/10.1002/ardp.202000163},
number = {1},
pages = {2000163},
doi = {10.1002/ardp.202000163}
}
MLA
Cite this
MLA Copy
Feng, Lian Shun, et al. “1,2,3‐Triazole hybrids with anti‐HIV‐1 activity.” Archiv der Pharmazie, vol. 354, no. 1, Sep. 2020, p. 2000163. https://doi.org/10.1002/ardp.202000163.