volume 13 issue 19 pages 5450-5465

Asymmetric Synthesis of Antimicrotubule Biaryl Hybrids of Allocolchicine and Steganacin

Agnès Joncour 1
Anne Décor 1
Jian-Miao Liu 1
Marie-Elise Tran Huu-Dau 1
Olivier Baudoin 2
1
 
Institut de Chimie des Substances Naturelles, CNRS, Avenue de la Terrasse, 91198 Gif sur Yvette, France.
2
 
ICBMS, Institut de Chimie et Biochimie Moléculaires et Supramoléculaires, 43 Boulevard du 11 Novembre 1918, Villeurbanne, 69622, France
Publication typeJournal Article
Publication date2007-06-25
scimago Q1
wos Q2
SJR0.981
CiteScore6.7
Impact factor3.7
ISSN09476539, 15213765
General Chemistry
Catalysis
Organic Chemistry
Abstract
Linking rings: A short enantioselective synthesis is used to obtain axially chiral natural product hybrids with promising antimicrotubule properties. The biaryl configuration was controlled by induction from a benzylic stereocenter in a diastereoselective Suzuki coupling. The medium ring of the target molecules was then installed by a SN1- or SN2-type cyclization with minimal loss of optical purity.
Found 
Found 

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GOST Copy
Joncour A. et al. Asymmetric Synthesis of Antimicrotubule Biaryl Hybrids of Allocolchicine and Steganacin // Chemistry - A European Journal. 2007. Vol. 13. No. 19. pp. 5450-5465.
GOST all authors (up to 50) Copy
Joncour A., Décor A., Liu J., Tran Huu-Dau M., Baudoin O. Asymmetric Synthesis of Antimicrotubule Biaryl Hybrids of Allocolchicine and Steganacin // Chemistry - A European Journal. 2007. Vol. 13. No. 19. pp. 5450-5465.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1002/chem.200601764
UR - https://doi.org/10.1002/chem.200601764
TI - Asymmetric Synthesis of Antimicrotubule Biaryl Hybrids of Allocolchicine and Steganacin
T2 - Chemistry - A European Journal
AU - Joncour, Agnès
AU - Décor, Anne
AU - Liu, Jian-Miao
AU - Tran Huu-Dau, Marie-Elise
AU - Baudoin, Olivier
PY - 2007
DA - 2007/06/25
PB - Wiley
SP - 5450-5465
IS - 19
VL - 13
PMID - 17352448
SN - 0947-6539
SN - 1521-3765
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2007_Joncour,
author = {Agnès Joncour and Anne Décor and Jian-Miao Liu and Marie-Elise Tran Huu-Dau and Olivier Baudoin},
title = {Asymmetric Synthesis of Antimicrotubule Biaryl Hybrids of Allocolchicine and Steganacin},
journal = {Chemistry - A European Journal},
year = {2007},
volume = {13},
publisher = {Wiley},
month = {jun},
url = {https://doi.org/10.1002/chem.200601764},
number = {19},
pages = {5450--5465},
doi = {10.1002/chem.200601764}
}
MLA
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MLA Copy
Joncour, Agnès, et al. “Asymmetric Synthesis of Antimicrotubule Biaryl Hybrids of Allocolchicine and Steganacin.” Chemistry - A European Journal, vol. 13, no. 19, Jun. 2007, pp. 5450-5465. https://doi.org/10.1002/chem.200601764.