Synthesis of Chromone-Containing Allylmorpholines through a Morita-Baylis-Hillman-Type Reaction
Тип публикации: Journal Article
Дата публикации: 2018-10-29
scimago Q2
wos Q2
БС2
SJR: 0.558
CiteScore: 4.3
Impact factor: 2.7
ISSN: 1434193X, 10990690
Organic Chemistry
Physical and Theoretical Chemistry
Краткое описание
The first example of an unusual addition of chromone‐substituted acrylic acid to enamines is described. The process shows high versatility concerning both enamines and chromones. The reaction is catalyzed by tertiary amines and is highly likely of Morita–Baylis–Hillman‐type. The described compounds show combined moderate inhibitory action on BChE and antagonism towards NMDA receptors which makes them a perspective group for the development of anti‐Alzheimer drugs.
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Chernov N. M. et al. Synthesis of Chromone-Containing Allylmorpholines through a Morita-Baylis-Hillman-Type Reaction // European Journal of Organic Chemistry. 2018. Vol. 2018. No. 45. pp. 6304-6313.
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Chernov N. M., Shutov R. V., Barygin O. I., Dron M. Y., Starova G. L., Kuzmich N. N., Yakovlev I. P. Synthesis of Chromone-Containing Allylmorpholines through a Morita-Baylis-Hillman-Type Reaction // European Journal of Organic Chemistry. 2018. Vol. 2018. No. 45. pp. 6304-6313.
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TY - JOUR
DO - 10.1002/ejoc.201801159
UR - https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.201801159
TI - Synthesis of Chromone-Containing Allylmorpholines through a Morita-Baylis-Hillman-Type Reaction
T2 - European Journal of Organic Chemistry
AU - Chernov, Nikita M
AU - Shutov, R V
AU - Barygin, Oleg I
AU - Dron, Mikhail Y
AU - Starova, G. L.
AU - Kuzmich, Nikolay N
AU - Yakovlev, Igor P
PY - 2018
DA - 2018/10/29
PB - Wiley
SP - 6304-6313
IS - 45
VL - 2018
SN - 1434-193X
SN - 1099-0690
ER -
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@article{2018_Chernov,
author = {Nikita M Chernov and R V Shutov and Oleg I Barygin and Mikhail Y Dron and G. L. Starova and Nikolay N Kuzmich and Igor P Yakovlev},
title = {Synthesis of Chromone-Containing Allylmorpholines through a Morita-Baylis-Hillman-Type Reaction},
journal = {European Journal of Organic Chemistry},
year = {2018},
volume = {2018},
publisher = {Wiley},
month = {oct},
url = {https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.201801159},
number = {45},
pages = {6304--6313},
doi = {10.1002/ejoc.201801159}
}
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MLA
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Chernov, Nikita M., et al. “Synthesis of Chromone-Containing Allylmorpholines through a Morita-Baylis-Hillman-Type Reaction.” European Journal of Organic Chemistry, vol. 2018, no. 45, Oct. 2018, pp. 6304-6313. https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.201801159.
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