Synthesis of Chromone-Containing Allylmorpholines through a Morita-Baylis-Hillman-Type Reaction
Nikita M Chernov
1
,
R V Shutov
1
,
Oleg I Barygin
2
,
Mikhail Y Dron
2
,
G. L. Starova
3
,
Nikolay N Kuzmich
4, 5
,
Publication type: Journal Article
Publication date: 2018-10-29
scimago Q2
wos Q2
SJR: 0.558
CiteScore: 4.3
Impact factor: 2.7
ISSN: 1434193X, 10990690
Organic Chemistry
Physical and Theoretical Chemistry
Abstract
The first example of an unusual addition of chromone‐substituted acrylic acid to enamines is described. The process shows high versatility concerning both enamines and chromones. The reaction is catalyzed by tertiary amines and is highly likely of Morita–Baylis–Hillman‐type. The described compounds show combined moderate inhibitory action on BChE and antagonism towards NMDA receptors which makes them a perspective group for the development of anti‐Alzheimer drugs.
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17
Total citations:
17
Citations from 2024:
5
(29.41%)
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MLA
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GOST
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Chernov N. M. et al. Synthesis of Chromone-Containing Allylmorpholines through a Morita-Baylis-Hillman-Type Reaction // European Journal of Organic Chemistry. 2018. Vol. 2018. No. 45. pp. 6304-6313.
GOST all authors (up to 50)
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Chernov N. M., Shutov R. V., Barygin O. I., Dron M. Y., Starova G. L., Kuzmich N. N., Yakovlev I. P. Synthesis of Chromone-Containing Allylmorpholines through a Morita-Baylis-Hillman-Type Reaction // European Journal of Organic Chemistry. 2018. Vol. 2018. No. 45. pp. 6304-6313.
Cite this
RIS
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TY - JOUR
DO - 10.1002/ejoc.201801159
UR - https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.201801159
TI - Synthesis of Chromone-Containing Allylmorpholines through a Morita-Baylis-Hillman-Type Reaction
T2 - European Journal of Organic Chemistry
AU - Chernov, Nikita M
AU - Shutov, R V
AU - Barygin, Oleg I
AU - Dron, Mikhail Y
AU - Starova, G. L.
AU - Kuzmich, Nikolay N
AU - Yakovlev, Igor P
PY - 2018
DA - 2018/10/29
PB - Wiley
SP - 6304-6313
IS - 45
VL - 2018
SN - 1434-193X
SN - 1099-0690
ER -
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BibTex (up to 50 authors)
Copy
@article{2018_Chernov,
author = {Nikita M Chernov and R V Shutov and Oleg I Barygin and Mikhail Y Dron and G. L. Starova and Nikolay N Kuzmich and Igor P Yakovlev},
title = {Synthesis of Chromone-Containing Allylmorpholines through a Morita-Baylis-Hillman-Type Reaction},
journal = {European Journal of Organic Chemistry},
year = {2018},
volume = {2018},
publisher = {Wiley},
month = {oct},
url = {https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.201801159},
number = {45},
pages = {6304--6313},
doi = {10.1002/ejoc.201801159}
}
Cite this
MLA
Copy
Chernov, Nikita M., et al. “Synthesis of Chromone-Containing Allylmorpholines through a Morita-Baylis-Hillman-Type Reaction.” European Journal of Organic Chemistry, vol. 2018, no. 45, Oct. 2018, pp. 6304-6313. https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.201801159.
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