Hepatotoxicity mechanisms of isoniazid: A mini-review
HOZEIFA M. HASSAN
1, 2
,
Hong-Li Guo
1
,
BASHIR A. YOUSEF
1, 3
,
Luyong Zhang
1, 4, 5
,
Zhenzhou Jiang
1, 6, 7
Publication type: Journal Article
Publication date: 2015-06-10
scimago Q2
wos Q2
SJR: 0.745
CiteScore: 6.6
Impact factor: 2.8
ISSN: 0260437X, 10991263
DOI:
10.1002/jat.3175
PubMed ID:
26095833
Toxicology
Abstract
Isoniazid (INH) is an antituberculosis drug associated with idiosyncratic liver injury in susceptible patients. INH-induced hepatotoxicity remains a significant clinical problem, but the underlying mechanisms are still unclear, despite the growing evidence that INH and/or its major metabolite, hydrazine, play an important role in hepatotoxicity.
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Metrics
65
Total citations:
65
Citations from 2025:
7
(10.77%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
HASSAN H. M. et al. Hepatotoxicity mechanisms of isoniazid: A mini-review // Journal of Applied Toxicology. 2015. Vol. 35. No. 12. pp. 1427-1432.
GOST all authors (up to 50)
Copy
HASSAN H. M., Guo H., YOUSEF B. A., Zhang L., Jiang Z. Hepatotoxicity mechanisms of isoniazid: A mini-review // Journal of Applied Toxicology. 2015. Vol. 35. No. 12. pp. 1427-1432.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1002/jat.3175
UR - https://doi.org/10.1002/jat.3175
TI - Hepatotoxicity mechanisms of isoniazid: A mini-review
T2 - Journal of Applied Toxicology
AU - HASSAN, HOZEIFA M.
AU - Guo, Hong-Li
AU - YOUSEF, BASHIR A.
AU - Zhang, Luyong
AU - Jiang, Zhenzhou
PY - 2015
DA - 2015/06/10
PB - Wiley
SP - 1427-1432
IS - 12
VL - 35
PMID - 26095833
SN - 0260-437X
SN - 1099-1263
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2015_HASSAN,
author = {HOZEIFA M. HASSAN and Hong-Li Guo and BASHIR A. YOUSEF and Luyong Zhang and Zhenzhou Jiang},
title = {Hepatotoxicity mechanisms of isoniazid: A mini-review},
journal = {Journal of Applied Toxicology},
year = {2015},
volume = {35},
publisher = {Wiley},
month = {jun},
url = {https://doi.org/10.1002/jat.3175},
number = {12},
pages = {1427--1432},
doi = {10.1002/jat.3175}
}
Cite this
MLA
Copy
HASSAN, HOZEIFA M., et al. “Hepatotoxicity mechanisms of isoniazid: A mini-review.” Journal of Applied Toxicology, vol. 35, no. 12, Jun. 2015, pp. 1427-1432. https://doi.org/10.1002/jat.3175.