Synthesis and Urease Inhibition Studies of Barbituric and Thiobarbituric Acid Derived Sulphonamides
Тип публикации: Journal Article
Дата публикации: 2011-08-01
scimago Q3
wos Q3
БС2
SJR: 0.337
CiteScore: 3.4
Impact factor: 1.5
ISSN: 00094536, 21926549
General Chemistry
Краткое описание
Various novel barbituric and thiobarbituric acid derived sulphonamides were synthesized in excellent yield via three components single pot reaction; and these were screened for in vitro urease inhibition studies against jack bean urease. The compounds 1-7 were found to exhibit a low to moderate activity whereas compounds 8-14 showed a significant activity (88.3-99.9% inhibition determined at 500 μM concentration). Structures of the synthesized compounds were confirmed by 1H-NMR, 13C-NMR, mass spectrometry and elemental analysis data.
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Rauf A. et al. Synthesis and Urease Inhibition Studies of Barbituric and Thiobarbituric Acid Derived Sulphonamides // Journal of the Chinese Chemical Society. 2011. Vol. 58. No. 4. pp. 528-537.
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Rauf A., Ahmed F., Qureshi A., Aziz-ur-Rehman, Khan A., Qadir M. I., Choudhary M., Chohan Z. H., Youssoufid M. H., Haddad T. B. Synthesis and Urease Inhibition Studies of Barbituric and Thiobarbituric Acid Derived Sulphonamides // Journal of the Chinese Chemical Society. 2011. Vol. 58. No. 4. pp. 528-537.
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TY - JOUR
DO - 10.1002/jccs.201190017
UR - https://doi.org/10.1002/jccs.201190017
TI - Synthesis and Urease Inhibition Studies of Barbituric and Thiobarbituric Acid Derived Sulphonamides
T2 - Journal of the Chinese Chemical Society
AU - Rauf, Abdur
AU - Ahmed, F.
AU - Qureshi, A.M.
AU - Aziz-ur-Rehman
AU - Khan, Ajmal
AU - Qadir, Muhammad I.
AU - Choudhary, M.I.
AU - Chohan, Z. H.
AU - Youssoufid, M H
AU - Haddad, T Ben
PY - 2011
DA - 2011/08/01
PB - Wiley
SP - 528-537
IS - 4
VL - 58
SN - 0009-4536
SN - 2192-6549
ER -
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@article{2011_Rauf,
author = {Abdur Rauf and F. Ahmed and A.M. Qureshi and Aziz-ur-Rehman and Ajmal Khan and Muhammad I. Qadir and M.I. Choudhary and Z. H. Chohan and M H Youssoufid and T Ben Haddad},
title = {Synthesis and Urease Inhibition Studies of Barbituric and Thiobarbituric Acid Derived Sulphonamides},
journal = {Journal of the Chinese Chemical Society},
year = {2011},
volume = {58},
publisher = {Wiley},
month = {aug},
url = {https://doi.org/10.1002/jccs.201190017},
number = {4},
pages = {528--537},
doi = {10.1002/jccs.201190017}
}
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MLA
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Rauf, Abdur, et al. “Synthesis and Urease Inhibition Studies of Barbituric and Thiobarbituric Acid Derived Sulphonamides.” Journal of the Chinese Chemical Society, vol. 58, no. 4, Aug. 2011, pp. 528-537. https://doi.org/10.1002/jccs.201190017.
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