Gold nanoparticles in ophthalmology
Publication type: Journal Article
Publication date: 2018-05-16
scimago Q1
wos Q1
SJR: 3.169
CiteScore: 29.5
Impact factor: 11.6
ISSN: 01986325, 10981128
PubMed ID:
29766541
Drug Discovery
Pharmacology
Molecular Medicine
Abstract
Many research projects are underway to improve the diagnosis and therapy in ophthalmology. Indeed, visual acuity deficits affect 285 million people worldwide and different strategies are being developed to strengthen patient care. One of these strategies is the use of gold nanoparticles (GNP) for their multiple properties and their ability to be used as both diagnosis and therapy tools. This review exhaustively details research developing GNPs for use in ophthalmology. The toxicity of GNPs and their distribution in the eye are described through in vitro and in vivo studies. All publications addressing the pharmacokinetics of GNPs administered in the eye are extensively reviewed. In addition, their use as biosensors or for imaging with optical coherence tomography is illustrated. The future of GNPs for ophthalmic therapy is also discussed. GNPs can be used to deliver genes or drugs through different administration routes. Their antiangiogenic and anti‐inflammatory properties are of great interest for different ocular pathologies. Finally, GNPs can be used to improve stereotactic radiosurgery, brachytherapy, and photothermal therapy because of their many properties.
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104
Total citations:
104
Citations from 2024:
32
(31.07%)
Cite this
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MLA
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GOST
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Masse F. et al. Gold nanoparticles in ophthalmology // Medicinal Research Reviews. 2018. Vol. 39. No. 1. pp. 302-327.
GOST all authors (up to 50)
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Masse F., Ouellette M., Lamoureux G., Boisselier E. Gold nanoparticles in ophthalmology // Medicinal Research Reviews. 2018. Vol. 39. No. 1. pp. 302-327.
Cite this
RIS
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TY - JOUR
DO - 10.1002/med.21509
UR - https://doi.org/10.1002/med.21509
TI - Gold nanoparticles in ophthalmology
T2 - Medicinal Research Reviews
AU - Masse, Florence
AU - Ouellette, Mathieu
AU - Lamoureux, Guillaume
AU - Boisselier, Elodie
PY - 2018
DA - 2018/05/16
PB - Wiley
SP - 302-327
IS - 1
VL - 39
PMID - 29766541
SN - 0198-6325
SN - 1098-1128
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2018_Masse,
author = {Florence Masse and Mathieu Ouellette and Guillaume Lamoureux and Elodie Boisselier},
title = {Gold nanoparticles in ophthalmology},
journal = {Medicinal Research Reviews},
year = {2018},
volume = {39},
publisher = {Wiley},
month = {may},
url = {https://doi.org/10.1002/med.21509},
number = {1},
pages = {302--327},
doi = {10.1002/med.21509}
}
Cite this
MLA
Copy
Masse, Florence, et al. “Gold nanoparticles in ophthalmology.” Medicinal Research Reviews, vol. 39, no. 1, May. 2018, pp. 302-327. https://doi.org/10.1002/med.21509.