volume 5 issue 8 pages 2581-2587

New Di(heteroaryl)ethenes as Apoptotic Anti‐proliferative Agents Towards Breast Cancer: Design, One‐Pot Synthesis and In Vitro Evaluation

Carmela M. Bonaccorso 1
Irina Naletova 2
Giorgia Spampinato 4, 5
Vincenza Barresi 4, 5
Cosimo G. Fortuna 1
Publication typeJournal Article
Publication date2020-02-26
scimago Q3
wos Q3
SJR0.366
CiteScore3.0
Impact factor2.0
ISSN23656549
General Chemistry
Abstract
Breast cancer resistance to traditional chemotherapeutics demands new drugs with novel mechanisms of action. Herein we report the drug design, synthesis and in-vitro biological evaluation against breast adenocarcinoma MCF-7 cell line that identified six compounds more effective than the well-know 5-FU. These results will also be useful for future pharmacokinetic studies and should be adaptable to the study of other class of compounds and other cancer cell lines.
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GOST Copy
M. Bonaccorso C. et al. New Di(heteroaryl)ethenes as Apoptotic Anti‐proliferative Agents Towards Breast Cancer: Design, One‐Pot Synthesis and In Vitro Evaluation // ChemistrySelect. 2020. Vol. 5. No. 8. pp. 2581-2587.
GOST all authors (up to 50) Copy
M. Bonaccorso C., Naletova I., Satriano C., Spampinato G., Barresi V., Fortuna C. G. New Di(heteroaryl)ethenes as Apoptotic Anti‐proliferative Agents Towards Breast Cancer: Design, One‐Pot Synthesis and In Vitro Evaluation // ChemistrySelect. 2020. Vol. 5. No. 8. pp. 2581-2587.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1002/slct.201903502
UR - https://doi.org/10.1002/slct.201903502
TI - New Di(heteroaryl)ethenes as Apoptotic Anti‐proliferative Agents Towards Breast Cancer: Design, One‐Pot Synthesis and In Vitro Evaluation
T2 - ChemistrySelect
AU - M. Bonaccorso, Carmela
AU - Naletova, Irina
AU - Satriano, Cristina
AU - Spampinato, Giorgia
AU - Barresi, Vincenza
AU - Fortuna, Cosimo G.
PY - 2020
DA - 2020/02/26
PB - Wiley
SP - 2581-2587
IS - 8
VL - 5
SN - 2365-6549
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2020_M. Bonaccorso,
author = {Carmela M. Bonaccorso and Irina Naletova and Cristina Satriano and Giorgia Spampinato and Vincenza Barresi and Cosimo G. Fortuna},
title = {New Di(heteroaryl)ethenes as Apoptotic Anti‐proliferative Agents Towards Breast Cancer: Design, One‐Pot Synthesis and In Vitro Evaluation},
journal = {ChemistrySelect},
year = {2020},
volume = {5},
publisher = {Wiley},
month = {feb},
url = {https://doi.org/10.1002/slct.201903502},
number = {8},
pages = {2581--2587},
doi = {10.1002/slct.201903502}
}
MLA
Cite this
MLA Copy
M. Bonaccorso, Carmela, et al. “New Di(heteroaryl)ethenes as Apoptotic Anti‐proliferative Agents Towards Breast Cancer: Design, One‐Pot Synthesis and In Vitro Evaluation.” ChemistrySelect, vol. 5, no. 8, Feb. 2020, pp. 2581-2587. https://doi.org/10.1002/slct.201903502.