Lembehyne A, a Spongean Polyacetylene, Induces Neuronal Differentiation in Neuroblastoma Cell
Publication type: Journal Article
Publication date: 2001-11-01
scimago Q2
wos Q3
SJR: 0.748
CiteScore: 4.9
Impact factor: 2.2
ISSN: 0006291X, 10902104
PubMed ID:
11716510
Biochemistry
Molecular Biology
Cell Biology
Biophysics
Abstract
Lembehyne A (LB-A), a spongean polyacetylene, induced neuronal cell differentiation in a neuroblastoma cell line, Neuro 2A. The LB-A treatment of Neuro 2A cells predominantly resulted in a morphological change with bipolar neurites. The acetylcholinesterase activity of Neuro 2A was also increased by the treatment of LB-A. Furthermore, the cell cycle of Neuro 2A cells was found to be specifically blocked at the G1 phase by LB-A. The structure-activity relationship study using the LB-A analogues revealed the importance of the terminal 1-yn-3-ol and unsaturated long-chain alkyl moieties for the neuronal differentiation activity of LB-A.
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Total citations:
33
Citations from 2024:
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(6.06%)
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MLA
Cite this
GOST
Copy
Aoki S. et al. Lembehyne A, a Spongean Polyacetylene, Induces Neuronal Differentiation in Neuroblastoma Cell // Biochemical and Biophysical Research Communications. 2001. Vol. 289. No. 2. pp. 558-563.
GOST all authors (up to 50)
Copy
Aoki S., Matsui K., Takata T., Hong W., Kobayashi M. Lembehyne A, a Spongean Polyacetylene, Induces Neuronal Differentiation in Neuroblastoma Cell // Biochemical and Biophysical Research Communications. 2001. Vol. 289. No. 2. pp. 558-563.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1006/bbrc.2001.6012
UR - https://doi.org/10.1006/bbrc.2001.6012
TI - Lembehyne A, a Spongean Polyacetylene, Induces Neuronal Differentiation in Neuroblastoma Cell
T2 - Biochemical and Biophysical Research Communications
AU - Aoki, Shunji
AU - Matsui, Kouhei
AU - Takata, Tetsuo
AU - Hong, Wei
AU - Kobayashi, Motomasa
PY - 2001
DA - 2001/11/01
PB - Elsevier
SP - 558-563
IS - 2
VL - 289
PMID - 11716510
SN - 0006-291X
SN - 1090-2104
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2001_Aoki,
author = {Shunji Aoki and Kouhei Matsui and Tetsuo Takata and Wei Hong and Motomasa Kobayashi},
title = {Lembehyne A, a Spongean Polyacetylene, Induces Neuronal Differentiation in Neuroblastoma Cell},
journal = {Biochemical and Biophysical Research Communications},
year = {2001},
volume = {289},
publisher = {Elsevier},
month = {nov},
url = {https://doi.org/10.1006/bbrc.2001.6012},
number = {2},
pages = {558--563},
doi = {10.1006/bbrc.2001.6012}
}
Cite this
MLA
Copy
Aoki, Shunji, et al. “Lembehyne A, a Spongean Polyacetylene, Induces Neuronal Differentiation in Neuroblastoma Cell.” Biochemical and Biophysical Research Communications, vol. 289, no. 2, Nov. 2001, pp. 558-563. https://doi.org/10.1006/bbrc.2001.6012.
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