Aragusterol C: A novel halogenated marine steroid from an Okinawan sponge,Xestospongia sp., possessing potent antitumor activity
H. Shimura
1
,
K. Iguchi
1
,
Y. Yamada
1
,
S Nakaike
2
,
T. YAMAGISHI
2
,
K Matsumoto
2
,
C. Yokoo
2
1
Tokyo College of Pharmacy, Tokyo, Japan
|
2
Research Center, Taisho Pharmaceutical Co., Ltd., Saitama, Japan
|
Publication type: Journal Article
Publication date: 1994-02-01
scimago Q1
wos Q1
SJR: 2.299
CiteScore: 12.5
Impact factor: 6.2
ISSN: 1420682X, 14209071
PubMed ID:
8125172
Molecular Biology
Pharmacology
Cell Biology
Molecular Medicine
Cellular and Molecular Neuroscience
Abstract
A novel chlorinated steroid, aragusterol C, was isolated from an Okinawan marine sponge of the genusXestospongia. The compound strongly inhibited the proliferation of KB cells in vitro, and also showed potent in vivo antitumor activity against L1210 cells in mice. The complete structure of aragusterol C was determined by spectroscopic analysis and X-ray crystallographic analysis.
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Total citations:
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Citations from 2024:
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GOST
Copy
Shimura H. et al. Aragusterol C: A novel halogenated marine steroid from an Okinawan sponge,Xestospongia sp., possessing potent antitumor activity // Cellular and Molecular Life Sciences. 1994. Vol. 50. No. 2. pp. 134-136.
GOST all authors (up to 50)
Copy
Shimura H., Iguchi K., Yamada Y., Nakaike S., YAMAGISHI T., Matsumoto K., Yokoo C. Aragusterol C: A novel halogenated marine steroid from an Okinawan sponge,Xestospongia sp., possessing potent antitumor activity // Cellular and Molecular Life Sciences. 1994. Vol. 50. No. 2. pp. 134-136.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1007/bf01984951
UR - https://doi.org/10.1007/bf01984951
TI - Aragusterol C: A novel halogenated marine steroid from an Okinawan sponge,Xestospongia sp., possessing potent antitumor activity
T2 - Cellular and Molecular Life Sciences
AU - Shimura, H.
AU - Iguchi, K.
AU - Yamada, Y.
AU - Nakaike, S
AU - YAMAGISHI, T.
AU - Matsumoto, K
AU - Yokoo, C.
PY - 1994
DA - 1994/02/01
PB - Springer Nature
SP - 134-136
IS - 2
VL - 50
PMID - 8125172
SN - 1420-682X
SN - 1420-9071
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{1994_Shimura,
author = {H. Shimura and K. Iguchi and Y. Yamada and S Nakaike and T. YAMAGISHI and K Matsumoto and C. Yokoo},
title = {Aragusterol C: A novel halogenated marine steroid from an Okinawan sponge,Xestospongia sp., possessing potent antitumor activity},
journal = {Cellular and Molecular Life Sciences},
year = {1994},
volume = {50},
publisher = {Springer Nature},
month = {feb},
url = {https://doi.org/10.1007/bf01984951},
number = {2},
pages = {134--136},
doi = {10.1007/bf01984951}
}
Cite this
MLA
Copy
Shimura, H., et al. “Aragusterol C: A novel halogenated marine steroid from an Okinawan sponge,Xestospongia sp., possessing potent antitumor activity.” Cellular and Molecular Life Sciences, vol. 50, no. 2, Feb. 1994, pp. 134-136. https://doi.org/10.1007/bf01984951.